VAL C SHEFFIELD, MD
Medical Practice at Hawkins Dr, Iowa City, IA

License number
Iowa 27730
Category
Medical Practice
Type
Clinical Genetics (M.D.)
Address
Address
200 Hawkins Dr, Iowa City, IA 52242
Phone
(319) 335-6898
(319) 335-7588 (Fax)

Organization information

See more information about VAL C SHEFFIELD at bizstanding.com

University Of Iowa Hosps CLNCS - Val C Sheffield MD

200 Hawkins Dr #C606, Iowa City, IA 52242

Categories:
Pediatrics Physicians & Surgeons
Phone:
(319) 356-8133 (Phone)

Professional information

Val Cowley Sheffield Photo 1

Val Cowley Sheffield, Iowa City IA

Specialties:
Medical Genetics, Clinical Molecular Genetics, Clinical Genetics, M.D., Pediatric Medical Genetics, Pediatrics
Work:
University Of Iowa Hospital & Clinic
200 Hawkins Dr, Iowa City, IA 52243
Education:
University of Chicago (1985)


Val Sheffield Photo 2

Therapeutics And Diagnostics For Congenital Heart Disease Based On A Novel Human Transcription Factor

US Patent:
6087107, Jul 11, 2000
Filed:
May 22, 1998
Appl. No.:
9/083351
Inventors:
Val C. Sheffield - Coralville IA
Wallace L. M. Alward - Iowa City IA
Edwin M. Stone - Iowa City IA
Darryl Nishimura - Coralville IA
Shiva Patil - Iowa City IA
Assignee:
The University of Iowa Research Foundation - Iowa City IA
International Classification:
C07H 2104, C12Q 168, G01N 3353
US Classification:
435 6
Abstract:
Methods and compositions for treating a congenital heart disease and methods and compositions for prognosing or diagnosing a congenital heart disease in a subject are disclosed.


Val Sheffield Photo 3

Macular Degeneration Diagnostics And Therapeutics

US Patent:
6593104, Jul 15, 2003
Filed:
May 28, 1999
Appl. No.:
09/322357
Inventors:
Edwin M. Stone - Iowa City IA
Val C. Sheffield - Coralville IA
Assignee:
University of Iowa Research Foundation - Iowa City IA
International Classification:
C12N 1500
US Classification:
435 691, 4353201, 435325, 435455, 536 231, 536 235
Abstract:
Therapeutics and diagnostics based on the identification of genetic mutations, which cause Macular Degeneration (MD) are disclosed.


Val Sheffield Photo 4

Methods To Identify Modulators Of Fkhl7 Dna-Binding Activity

US Patent:
6833239, Dec 21, 2004
Filed:
Jul 10, 2000
Appl. No.:
09/612809
Inventors:
Val C. Sheffield - Coralville IA
Wallace L. M. Alward - Iowa City IA
Edwin M. Stone - Iowa City IA
Darryl Nishimura - Coralville IA
Shiva Patil - Iowa City IA
Assignee:
The University of Iowa Research Foundation - Iowa City IA
International Classification:
C12Q 168
US Classification:
435 6, 435 4, 435 71, 4353201, 4352351, 435 691, 536 231, 536 241, 530350
Abstract:
Methods and compositions for treating a congenital heart disease and methods and compositions for prognosing or diagnosing a congenital heart disease in a subject are disclosed.


Val Sheffield Photo 5

Glaucoma Therapeutics And Diagnostics

US Patent:
6403307, Jun 11, 2002
Filed:
Apr 7, 1998
Appl. No.:
09/056285
Inventors:
Edwin M. Stone - Iowa City IA
Val C. Sheffield - Coralville IA
Wallace L. M. Alward - Iowa City IA
John Fingert - Iowa City IA
Assignee:
University of Iowa Research Foundation - Iowa City IA
International Classification:
C12Q 168
US Classification:
435 6, 435 912, 536 231, 536 243
Abstract:
Methods and compositions for preventing and treating glaucoma; and glaucoma diagnostics are disclosed.


Val Sheffield Photo 6

Bardet-Biedl Susceptibility Gene And Uses Thereof

US Patent:
7947479, May 24, 2011
Filed:
Mar 7, 2006
Appl. No.:
11/370242
Inventors:
Val Sheffield - Iowa City IA, US
Darryl Nishimura - Coralville IA, US
Edwin Stone - Iowa City IA, US
Assignee:
The University of Iowa Research Foundation - Iowa City IA
International Classification:
C12Q 1/68
US Classification:
435183, 435325, 435456
Abstract:
The present invention relates to the identification of a gene, now designated negevin (ngvn), that is involved in the genetic disease Bardet Biedl Syndrome (BBS), which is characterized by such diverse symptoms as obesity, diabetes, hypertension, mental retardation, renal cancer and other abnormalities, retinopathy and hypogonadism. The human NGVN protein disclosed herein is 731 amino acids in length and is coded for by a gene spanning 17 exons. Homologs have been identified in mouse, rat, zebrafish. Methods of use for the gene, for example in diagnosis and therapy of BBS and in drug screening, also are described.


Val Sheffield Photo 7

Bardet-Biedl Susceptibility Gene And Uses Thereof

US Patent:
8129161, Mar 6, 2012
Filed:
Oct 20, 2010
Appl. No.:
12/908707
Inventors:
Val Sheffield - Iowa City IA, US
Darryl Nishimura - Coralville IA, US
Edwin Stone - Iowa City IA, US
Assignee:
The University of Iowa Research Foundation - Iowa City IA
International Classification:
C12N 15/63
US Classification:
435183, 4353201, 536 235
Abstract:
The present invention relates to the identification of a gene, now designated negevin (ngvn), that is involved in the genetic disease Bardet Biedl Syndrome (BBS), which is characterized by such diverse symptoms as obesity, diabetes, hypertension, mental retardation, renal cancer and other abnormalities, retinopathy and hypogonadism. The human NGVN protein disclosed herein is 731 amino acids in length and is coded for by a gene spanning 17 exons. Homologs have been identified in mouse, rat, zebrafish. Methods of use for the gene, for example in diagnosis and therapy of BBS and in drug screening, also are described.


Val Sheffield Photo 8

Glaucoma Compositions And Therapeutic And Diagnositic Uses Therefor

US Patent:
5885776, Mar 23, 1999
Filed:
Jan 30, 1997
Appl. No.:
8/791347
Inventors:
Edwin M. Stone - Iowa City IA
Val C. Sheffield - Coralville IA
Wallace L. M. Alward - Iowa City IA
Assignee:
University of Iowa Research Foundation - Iowa City IA
International Classification:
C12Q 168
US Classification:
435 6
Abstract:
Methods and compositions for treating glaucoma; and glaucoma diagnostics are disclosed.


Val Sheffield Photo 9

Dna Diagnostics For Glaucoma

US Patent:
5925748, Jul 20, 1999
Filed:
Nov 8, 1996
Appl. No.:
8/748479
Inventors:
Edwin M. Stone - Iowa City IA
Val C. Sheffield - Coralville IA
Wallace L.M. Alward - Iowa City IA
Assignee:
The University of Iowa Research Foundation - Iowa City IA
International Classification:
C07H 2102, C07H 2104, C07H 1900, C07H 2100
US Classification:
536 231
Abstract:
Methods and kits for diagnosing a subject with glaucoma or with a predisposition for developing glaucoma are disclosed.


Val Sheffield Photo 10

Macular Degeneration Diagnostics And Therapeutics

US Patent:
2003013, Jul 24, 2003
Filed:
Jul 8, 2002
Appl. No.:
10/191676
Inventors:
Edwin Stone - Iowa City IA, US
Val Sheffield - Coralville IA, US
Assignee:
University of Iowa Research Foundation
International Classification:
C12Q001/68, G01N033/567
US Classification:
435/006000, 435/007210
Abstract:
Therapeutics and diagnostics based on the identification of genetic mutations, which cause Macular Degeneration (MD) is disclosed.