UGUR SALLI
Veterinary in Hummelstown, PA
License number
Pennsylvania BV013021
Category
Veterinary Medicine
Type
Veterinarian
Address
Address
Hummelstown, PA 17036
Professional information
Systems And Methods For Selection And Maintenance Of Homogeneous And Pluripotent Human Embryonic Stem Cells
US Patent:
7754483, Jul 13, 2010
Filed:
Nov 8, 2006
Appl. No.:
11/557791
Inventors:
Ugur Salli - Hummelstown PA, US
Mark Kester - Harrisburg PA, US
Kent E. Vrana - Hummelstown PA, US
Mark Kester - Harrisburg PA, US
Kent E. Vrana - Hummelstown PA, US
Assignee:
The Penn State Research Foundation - University Park PA
International Classification:
C12N 5/00
US Classification:
435377, 435325, 435375
Abstract:
A number of human disorders are characterized by degeneration or loss of specific cells, resulting in pathology associated with reduction or absence of cell function. Such diseases include neurodegenerative diseases and diabetes. Methods are described for obtaining a substantially homogeneous population of undifferentiated human embryonic stem cells including incubating a population of human embryonic stem cells with an amount of a selection agent. The selection agent is effective to reduce or eliminate differentiated embryonic stem cells from the population of cells such that a substantially homogeneous population of undifferentiated human embryonic stem cells is obtained. The substantially homogeneous population of undifferentiated embryonic stem cells may be produced without use of feeder cells.