Inventors:
Paul Bird - Edmonton, CA
Edmund Lee Ellsworth - Brighton MI, US
Dai Quoc Nguyen - Edmonton, CA
Joseph Peter Sanchez - South Lyon MI, US
Howard Daniel Hollis Showalter - Ann Arbor MI, US
Rajeshwar Singh - Edmonton, CA
Michael Andrew Stier - Ypsilanti MI, US
Tuan Phong Tran - Canton MI, US
Brian Morgan Watson - Carmel IN, US
Judy Yip - Edmonton, CA
Assignee:
Warner-Lambert Company - Morris Plains NJ
International Classification:
C07D 487/04
US Classification:
5142285, 5142342, 51425216, 5142641, 544 61, 544117, 544279
Abstract:
Antibacterial 3-aminoquinazolin-2,4-diones have formula (I) wherein: Rand Rinclude alkyl, alkenyl, alkynyl, cycloalkyl, aryl, heterocyclic, and heteroaryl; R, R, and Rinclude H, alkyl, alkoxy, halo, NO, CN, NH, alkyl and dialkylamino; Rincludes hydrogen, alkyl, cycloalkyl, heterocyclic, fused heterocyclic, aryl and fused aryl; J and K are C or N; and pharmaceutically acceptable salts thereof.