TIMOTHY ROBERT BILLIAR
Medical Practice in Pittsburgh, PA

License number
Pennsylvania MD040947E
Category
Medicine
Type
Medical Physician and Surgeon
Address
Address
Pittsburgh, PA 15213

Professional information

Timothy R Billiar Photo 1

Dr. Timothy R Billiar, Pittsburgh PA - MD (Doctor of Medicine)

Specialties:
General Surgery
Address:
200 Lothrop St STE F1281, Pittsburgh 15213
(412) 647-0635 (Phone)
UPMC HLTH SYS RADIOLOGY DEPT
200 Lothrop St, Pittsburgh 15213
(412) 647-2345 (Phone), (412) 692-4825 (Fax)
545 Barnhill Dr, Indianapolis 46202
(412) 647-0635 (Phone)
Procedures:
Laparotomy, Trigger Point Injections
Conditions:
Diaphragmatic/Hiatal Hernia, Intestinal Obstruction, Peripheral Arterial Aneurysm and Dissection, Peripheral Vascular Disease (PAD, PVD), Rib Fracture, Ventral Hernia
Languages:
English
Education:
Medical School
U Of Chgo Div Of Bio Sci Pritzker Sch Of Med
Graduated: 1983


Timothy Billiar Photo 2

Timothy Billiar, Pittsburgh PA

Work:
Presb U Hosp.
200 Lothrop St, Pittsburgh, PA 15213 Emerson Hall
545 Barnhill Dr, Indianapolis, IN 46202


Timothy R Billiar Photo 3

Timothy R Billiar, Pittsburgh PA

Specialties:
Surgeon
Address:
200 Lothrop St, Pittsburgh, PA 15213
Board certifications:
American Board of Surgery Certification in Surgery


Timothy Billiar Photo 4

Methods For Promoting Wound Healing And Treating Transplant-Associated Vasculopathy

US Patent:
6103230, Aug 15, 2000
Filed:
Oct 2, 1998
Appl. No.:
9/165882
Inventors:
Timothy R. Billiar - Pittsburgh PA
Edith Tzeng - Pittsburgh PA
Larry L. Shears - Bethel Park PA
David A. Geller - Pittsburgh PA
Howard David James Edington - Pittsburgh PA
Assignee:
University of Pittsburgh of the Commonwealth System of Higher Education - Pittsburgh PA
International Classification:
A61K 3844, C12N 902, C12N 1553, C12N 1585
US Classification:
424 944
Abstract:
The present invention provides a method of promoting the closure of a wound in a patient. This method involves transferring exogenous iNOS to the region of the wound whereby a product of iNOS is produced in the region of the wound to promote the closure of the wound. The present invention also provides a method of transplanting a graft into a patient, which method involves transferring a vector comprising an iNOS expression cassette to cells associated with the graft and surgically incorporating the graft tissue into the patient. Upon expression of iNOS within the patient, a product of iNOS is produced in the region of the graft to attenuate vasculopathy in the region of the graft.


Timothy Billiar Photo 5

Isolated Human Inducible Nitric Oxide Synthase

US Patent:
5882908, Mar 16, 1999
Filed:
Jun 5, 1995
Appl. No.:
8/465522
Inventors:
Timothy R.. Billiar - Pittsburgh PA
Andreas K. Nussler - Pittsburgh PA
David A. Geller - Pittsburgh PA
Richard L. Simmons - Pittsburgh PA
Assignee:
University of Pittsburgh of the Commonwealth System of Higher Education - Pittsburgh PA
International Classification:
C12N 902, C12N 1553, C12N 1570
US Classification:
435189
Abstract:
A human tissue inducible nitric oxide synthase cDNA clone is disclosed. A process for preparing this cDNA clone coding for human tissue inducible nitric oxide synthase and for expressing the human tissue inducible nitric oxide synthase protein are provided.


Timothy Billiar Photo 6

Inducible Nitric Oxide Synthase Gene For Treatment Of Disease

US Patent:
5658565, Aug 19, 1997
Filed:
Jun 24, 1994
Appl. No.:
8/265046
Inventors:
Timothy R. Billiar - Pittsburgh PA
Edith Tzeng - Pittsburgh PA
Andreas K. Nussler - Neu-Ulm, DE
David A. Geller - Pittsburgh PA
Richard L. Simmons - Pittsburgh PA
Assignee:
University of Pittsburgh of the Commonwealth System of Higher Education - Pittsburgh PA
International Classification:
A61K 4800
US Classification:
424 9321
Abstract:
The present invention discloses a full-length human hepatocyte iNOS cDNA clone and various gene therapy applications utilizing an iNOS DNA sequence. In preferred embodiments of the disclosed invention, iNOS-directed gene therapy involves specific targeting of a DNA sequence encoding a protein or protein fragment with iNOS biological activity for treating vascular diseases and disorders, antitumor applications and in response to certain microbial infections.


Timothy Billiar Photo 7

Cdna Clone For Human Inducible Nitric Oxide Synthase And Process For Preparing Same

US Patent:
5468630, Nov 21, 1995
Filed:
Sep 28, 1994
Appl. No.:
8/314917
Inventors:
Timothy R. Billiar - Pittsburgh PA
Andreas K. Nussler - Pittsburgh PA
David A. Geller - Pittsburgh PA
Richard L. Simmons - Pittsburgh PA
Assignee:
University of Pittsburg of the Commonwealth System of Higher Education - Pittsburgh PA
International Classification:
C12N 902, C12N 1553, C12N 1570, C12N 1579
US Classification:
435189
Abstract:
A human tissue inducible nitric oxide synthase cDNA clone is disclosed. A process for preparing this cDNA clone coding for human tissue inducible nitric oxide synthase and for expressing the human tissue inducible nitric oxide synthase protein are provided.


Timothy Billiar Photo 8

Selective Prevention Of Organ Injury In Sepsis And Shock Using Selection Release Of Nitric Oxide In Vulnerable Organs

US Patent:
5714511, Feb 3, 1998
Filed:
Jul 31, 1995
Appl. No.:
8/509558
Inventors:
Joseph E. Saavedra - Thurmont MD
Larry K. Keefer - Bethesda MD
Timothy R. Billiar - Pittsburgh PA
Assignee:
The United States of America as represented by the Secretary of the
Department of Health and Human Services - Washington DC
The University of Pittsburgh - Pittsburgh PA
International Classification:
A61K 3140, A61K 31655, A61K 31535, A61K 31495, A61K 3147, A61K 3128, A61K 31315, A61K 3130, A61K 3120, A61K 31195, A61K 3118, A61K 3104, A61K 3113, A61K 31135
US Classification:
514426
Abstract:
A method for the treatment of mammalian tissue injured or at risk of injury during sepsis or shock including the administration to a mammal a diazeniumdiolate which releases a therapeutically effective amount of nitric oxide sufficient to protect the tissue from sepsis- or shock-induced injury.


Timothy Billiar Photo 9

Methods For Promoting Wound Healing And Treating Transplant-Associated Vasculopathy

US Patent:
5830461, Nov 3, 1998
Filed:
Nov 8, 1996
Appl. No.:
8/745375
Inventors:
Timothy R. Billiar - Pittsburgh PA
Edith Tzeng - Pittsburgh PA
Larry L. Shears - Bethel Park PA
David A. Geller - Pittsburgh PA
Howard David James Edington - Pittsburgh PA
Assignee:
University of Pittsburgh of the Commonwealth System of Higher Education - Pittsburgh PA
International Classification:
A61K 3844, C12N 902
US Classification:
424 944
Abstract:
The present invention provides a method of promoting the closure of a wound in a patient. This method involves transferring exogenous iNOS to the region of the wound whereby a product of iNOS is produced in the region of the wound to promote the closure of the wound.