Inventors:
Craig M. Stolen - New Brighton MN, US
Timothy E. Meyer - North Oaks MN, US
Milan Seth - Minneapolis MN, US
Francis G. Spinale - Blythewood SC, US
Nicholas David Wold - Arden Hills MN, US
Assignee:
MEDICAL UNIVERSITY OF SOUTH CAROLINA - Charleston SC
CARDIAC PACMAKERS, INC. - St. Paul MN
International Classification:
A61B 5/145, A61N 1/365, A61B 5/00
US Classification:
506 9, 435 792, 436501, 435 612, 600309, 204450
Abstract:
Embodiments of the disclosure are related to systems and methods for utilizing biomarker panel data and related medical devices and methods, amongst other things. An embodiment can include a method of screening patients. The method can include quantifying levels of one or more of a panel of biomarkers in a biological sample of a patient. The method can further include analyzing the quantified levels. In some embodiments, the panel of biomarkers includes at least two selected from the group consisting of CRP, SGP-130, sIL-2R, sTNFR-II, IFNg, BNP, sST2, MMP-2, MMP-9, TIMP-1, TIMP-2, TIMP-4. In an embodiment, the disclosure can include a method of diagnosing a patient. The method can include quantifying levels of one or more of a panel of biomarkers in a biological sample of a patient. The method can further include diagnosing the patient based at least in part on the quantified levels. In some embodiments, the panel of biomarkers includes at least two selected from the group consisting of CRP, SGP-130, sIL-2R, sTNFR-II, IFNg, BNP, sST2, MMP-2, MMP-9, TIMP-1, TIMP-2, TIMP-4. Other embodiments are also included herein.