DR. TIMOTHY HAMMOND, MD
Osteopathic Medicine at Tulane Ave, New Orleans, LA
License number
Louisiana 11582R
Category
Osteopathic Medicine
Type
Nephrology
Address
Address
1415 Tulane Ave, New Orleans, LA 70112
Phone
(504) 988-2300
(504) 988-8886 (Fax)
(504) 988-8886 (Fax)
Professional information
See more information about TIMOTHY HAMMOND at trustoria.com
Timothy G Hammond, New Orleans LA
Timothy G Hammond, New Orleans LA
Specialties:
Internist
Address:
1415 Tulane Ave, New Orleans, LA 70112
508 Fulton St, Durham, NC 27705
508 Fulton St, Durham, NC 27705
Education:
University of Melbourne, Faculty of Medicine, Dentistry and Health Sciences - Doctor of Medicine
Board certifications:
American Board of Internal Medicine Certification in Internal Medicine
Dr. Timothy Hammond - MD (Doctor of Medicine)
Dr. Timothy Hammond - MD (Doctor of Medicine)
Hospitals:
1415 Tulane Ave, New Orleans 70112
1415 Tulane Ave, New Orleans 70112
1415 Tulane Ave, New Orleans 70112
Education:
Medical Schools
University Of Melbourne, School Of Medicine
Graduated: 1981
University Of Melbourne, School Of Medicine
Graduated: 1981
Production Of Functional Proteins: Balance Of Shear Stress And Gravity
Production Of Functional Proteins: Balance Of Shear Stress And Gravity
US Patent:
6730498, May 4, 2004
Filed:
Apr 7, 1998
Appl. No.:
09/056363
Inventors:
Thomas John Goodwin - Friendswood TX
Timothy Grant Hammond - New Orleans LA
James Howard Kaysen - New Orleans LA
Timothy Grant Hammond - New Orleans LA
James Howard Kaysen - New Orleans LA
Assignee:
The United States of America as represented by the Administrator of the National Aeronautics and Space Administration - Washington DC
International Classification:
C12P 2106
US Classification:
435 691, 435 701, 435 703, 435375, 435394, 435383, 435403
Abstract:
The present invention provides a method for production of functional proteins including hormones by renal cells in a three dimensional co-culture process responsive to shear stress using a rotating wall vessel. Natural mixture of renal cells expresses the enzyme 1-a-hydroxylase which can be used to generate the active form of vitamin D: 1,25-diOH vitamin D3. The fibroblast cultures and co-culture of renal cortical cells express the gene for erythropoietin and secrete erythropoietin into the culture supernatant. Other shear stress response genes are also modulated by shear stress, such as toxin receptors megalin and cubulin (gp280). Also provided is a method of treating in-need individual with the functional proteins produced in a three dimensional co-culture process responsive to shear stress using a rotating wall vessel.
Cubilin Protein, Dna Sequences Encoding Cubilin And Uses Thereof
Cubilin Protein, Dna Sequences Encoding Cubilin And Uses Thereof
US Patent:
6586389, Jul 1, 2003
Filed:
Jul 20, 2000
Appl. No.:
09/341461
Inventors:
Pierre J. Verroust - Paris, FR
Timothy G. Hammond - New Orleans LA
Timothy G. Hammond - New Orleans LA
Assignee:
Administrators of the Tulane Educational Fund - New Orleans LA
International Classification:
A61K 3817
US Classification:
514 2, 530350
Abstract:
The present invention provides novel renal receptors for ligands. Cubilin and megalin are representative examples of such renal receptors. Also provided are potential uses of these renal receptors for treating toxicity in various tissues and for detecting renal damage.
Methods For Modeling Infectious Disease And Chemosensitivity In Cultured Cells And Tissues
Methods For Modeling Infectious Disease And Chemosensitivity In Cultured Cells And Tissues
US Patent:
7244578, Jul 17, 2007
Filed:
Apr 5, 2002
Appl. No.:
10/474075
Inventors:
Timothy Grant Hammond - New Orleans LA, US
Cheryl Anne Nickerson - River Ridge LA, US
Cheryl Anne Nickerson - River Ridge LA, US
Assignee:
Department of Veterans Affairs - Washington DC
Administrators of the Tulane Education Fund - New Orleans LA
Administrators of the Tulane Education Fund - New Orleans LA
International Classification:
C12Q 1/70
US Classification:
435 721, 435 5, 435 701, 435 703
Abstract:
The present invention provides methods for utilizing a form of optimized suspension culture to examine the infectivity of pathogenic organisms and agents in human cells and tissues. Also provided are methods using a rotating wall vessel to predict chemosensitivity of cells and tissues to toxins and chemotherapeutic agents. These culture conditions potentiate spatial colocalization and three-dimensional assembly of individual cells into large aggregates which more closely resemble the in vivo tissue equivalent. In this environment, dissociated cells can assemble and differentiate into macroscopic tissue aggregates several millimeters in size. These culture conditions allow for better cellular differentiation and formation of three-dimensional cellular aggregates, more efficient cell-to-cell interactions, the in in vivo-like exchange of growth factors and greater molecular scaffolding facilitating mechanical stability for cells. The suspension culture system offers a new approach for studying microbial infectivity from the perspective of the host-pathogen interaction and also for analyzing chemosensitivity to toxins and chemotherapeutic agents.
Production Of Functional Proteins: Balance Of Shear Stress And Gravity
Production Of Functional Proteins: Balance Of Shear Stress And Gravity
US Patent:
7972821, Jul 5, 2011
Filed:
Jul 16, 2008
Appl. No.:
12/174221
Inventors:
Thomas John Goodwin - Friendswood TX, US
Timothy Grant Hammond - New Orleans LA, US
James Howard Kaysen - New Orleans LA, US
Timothy Grant Hammond - New Orleans LA, US
James Howard Kaysen - New Orleans LA, US
Assignee:
The United States of America as represented by the Administrator of the National Aeronautics and Space Administration - Washington DC
International Classification:
C12P 15/00, C12Q 1/00, C12M 1/00, C12N 5/071
US Classification:
435127, 435 4, 4352831, 435369, 435371
Abstract:
A method for the production of functional proteins including hormones by renal cells in a three dimensional culturing process responsive to shear stress uses a rotating wall vessel. Natural mixture of renal cells expresses the enzyme 1-α-hydroxylase which can be used to generate the active form of vitamin D: 1,25-diOH vitamin D. The fibroblast cultures and co-culture of renal cortical cells express the gene for erythropoietin and secrete erythropoietin into the culture supernatant. Other shear stress response genes are also modulated by shear stress, such as toxin receptors megalin and cubulin (gp280). Also provided is a method of treating an in-need individual with the functional proteins produced in a three dimensional co-culture process responsive to shear stress using a rotating wall vessel.
Production Of Functional Proteins: Balance Of Shear Stress And Gravity
Production Of Functional Proteins: Balance Of Shear Stress And Gravity
US Patent:
7198947, Apr 3, 2007
Filed:
Dec 11, 2003
Appl. No.:
10/734759
Inventors:
Thomas John Goodwin - Friendswood TX, US
Timothy Grant Hammond - New Orleans LA, US
James Howard Kaysen - New Orleans LA, US
Timothy Grant Hammond - New Orleans LA, US
James Howard Kaysen - New Orleans LA, US
Assignee:
The United States of America as represented by the Administrator of the National Aeronautics and Space Administration - Washington DC
International Classification:
C12N 5/08
US Classification:
435369, 435 703, 435 701, 435189, 435325, 435366, 435383, 435403
Abstract:
The present invention provides a method for production of functional proteins including hormones by renal cells in a three dimensional co-culture process responsive to shear stress using a rotating wall vessel. Natural mixture of renal cells expresses the enzyme 1-a-hydroxylase which can be used to generate the active form of vitamin D: 1,25-diOH vitamin D3. The fibroblast cultures and co-culture of renal cortical cells express the gene for erythropoietin and secrete erythropoietin into the culture supernatant. Other shear stress response genes are also modulated by shear stress, such as toxin receptors megalin and cubulin (gp280). Also provided is a method of treating in-need individual with the functional proteins produced in a three dimensional co-culture process responsive to shear stress using a rotating wall vessel.
Methods For Modeling Infectious Disease And Chemosensitivity In Cultured Cells And Tissues
Methods For Modeling Infectious Disease And Chemosensitivity In Cultured Cells And Tissues
US Patent:
2010002, Feb 4, 2010
Filed:
Jul 16, 2007
Appl. No.:
11/778552
Inventors:
Timothy Grant Hammond - New Orleans LA, US
Cheryl Anne Nickerson - Phoenix AZ, US
Cheryl Anne Nickerson - Phoenix AZ, US
International Classification:
C12Q 1/70, C12Q 1/02, C12Q 1/68
US Classification:
435 5, 435 29, 435 6
Abstract:
The present invention provides methods for utilizing a form of optimized suspension culture to examine the infectivity of pathogenic organisms and agents in human cells and tissues. Also provided are methods using a rotating wall vessel to predict Chemosensitivity of cells and tissues to toxins and chemotherapeutic agents. These culture conditions potentiate spatial colocalization and three-dimensional assembly of individual cells into large aggregates which more closely resemble the in vivo tissue equivalent. In this environment, dissociated cells can assemble and differentiate into macroscopic tissue aggregates several millimeters in size. These culture conditions allow for better cellular differentiation and formation of three-dimensional cellular aggregates, more efficient cell-to-cell interactions, the in in vivo-like exchange of growth factors and greater molecular scaffolding facilitating mechanical stability for cells. The suspension culture system offers a new approach for studying microbial infectivity from the perspective of the host-pathogen interaction and also for analyzing chemosensitivity to toxins and chemotherapeutic agents.
Production Of Urokinase In A Three-Dimensional Cell Culture
Production Of Urokinase In A Three-Dimensional Cell Culture
US Patent:
7361493, Apr 22, 2008
Filed:
May 26, 2005
Appl. No.:
11/139102
Inventors:
Timothy G. Hammond - New Orleans LA, US
Patricia L. Allen - New Orleans LA, US
Patricia L. Allen - New Orleans LA, US
Assignee:
The United States of America as represented by the Secretary of the Department of Veterans Affairs - Washington DC
Tulane University - New Orleans LA
Tulane University - New Orleans LA
International Classification:
C12N 9/12
US Classification:
435194, 435212
Abstract:
Embodiments of a method for the production of human urokinase are disclosed. Also disclosed are embodiments of a cell culture well-suited for use with the disclosed method. The method involves culturing urokinase-producing cells, such as immortalized human renal cells, in a cell culture. The cell culture comprises microcarrier structures and a tissue culture medium. The urokinase production is allowed to occur while the cell culture remains relatively static, i. e. , the cell culture is not substantially mixed.
Production Of Functional Proteins: Balance Of Shear Stress And Gravity
Production Of Functional Proteins: Balance Of Shear Stress And Gravity
US Patent:
2006013, Jun 22, 2006
Filed:
Sep 20, 2004
Appl. No.:
10/947786
Inventors:
Thomas Goodwin - Friendswood TX, US
Timothy Hammond - New Orleans LA, US
James Kaysen - New Orleans LA, US
Timothy Hammond - New Orleans LA, US
James Kaysen - New Orleans LA, US
Assignee:
NASA, Johnson Space Center - Houston TX
International Classification:
C12P 33/00, C12P 21/06, C12N 15/87
US Classification:
435052000, 435069100, 435455000
Abstract:
The present invention provides for a method of culturing cells and inducing the expression of at least one gene in the cell culture. The method provides for contacting the cell with a transcription factor decoy oligonucleotide sequence comprising a nucleotide sequence encoding a shear stress response element.