DR. TIMOTHY E MOREY, MD
Anesthesiologist Assistant at Archer Rd, Gainesville, FL

6623765, Sep 23, 2003

Aug 1, 2000

09/630237

Donn M. Dennis - Gainesville FL
Nikolaus Gravenstein - Gainesville FL
Jerome H. Modell - Gainesville FL
Timothy E. Morey - Gainesville FL
Dinesh Shah - Gainesville FL

University of Florida, Research Foundation, Incorporated - Gainesville FL

A61K 950

424502, 424489, 424484, 424422, 424423, 5147721

A microemulsion delivery system for water insoluble or sparingly water soluble drugs that comprises a long polymer chain surfactant component and a short fatty acid surfactant component, with the amount of each being selected to provide stable microemulsion or micellar systems.

6638537, Oct 28, 2003

Aug 8, 2001

09/924290

Donn M. Dennis - Gainesville FL
Nikolaus Gravenstein - Gainesville FL
Jerome H. Modell - Gainesville FL
Timothy E. Morey - Gainesville FL
Dinesh Shah - Gainesville FL

University of Florida - Gainesville FL

A61K 950

424502, 424400, 424484, 424486, 424489, 424501, 424500

A microemulsion delivery system for water insoluble or sparingly water soluble drugs that comprises a long polymer chain surfactant component and a short fatty acid surfactant component, with the amount of each being selected to provide stable microemulsion or micellar systems.

2009000, Jan 1, 2009

Sep 20, 2005

11/578323

Richard J. Melker - Gainesville FL, US
Timothy E. Morey - Gainesville FL, US
Laszlo Prokai - Mansfield TX, US
Donn M. Dennis - Gainesville FL, US

UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. - Gainesville FL

C40B 60/12, C12Q 1/00, C12M 1/00

506 39, 435 4, 4352871, 4352879, 4352887

The present invention provides systems and methods for determining enzymatic competency, which is important in determining whether a patient may suffer an adverse drug reaction, has a disease associated with defects in specific enzymatic function, and/or has an enzyme defect that is likely to cause pathophysiology. As contemplated herein, a parent molecular entity is administered to a patient in whom enzymatic competency is to be determined. A sample of the patient's bodily fluid is exposed to a sensor of the invention to distinguish, detect, and quantify a detectable entity in the bodily fluid. Sensor-acquired data regarding the detectable entity is used to determine enzymatic competency. Preferably, a sample of a patient's exhaled breath is collected and exposed to the sensor of the invention. Types of sensor systems of the invention include, but are not limited to, surface resonance arrays; microelectromechanical sensors (such as microcantilever-based technology); molecularly imprinted polymer sensors; amplifying fluorescent sensor technology; aptamer-based sensor technology; SAW sensors; infrared sensors; fuel cells; chemical reactors; and pH sensitive sensors.

6977171, Dec 20, 2005

Oct 16, 2001

09/978344

Donn M. Dennis - Gainesville FL, US
Charles R. Martin - Gainesville FL, US
Timothy E. Morey - Gainesville FL, US
Richard E. Partch - Gainesville FL, US
Dinesh O Shah - Gainesville FL, US
Manoj Varshney - Gainesville FL, US

University of Florida - Gainesville FL

B09B003/00, A61K009/16, A01N025/00

4352625, 424401, 424484, 424497, 514937, 514938, 514939

A particle with two regions, the first region contains a detoxifying enzyme and a second region that partitions toxic compounds. The particle may be a nanoparticle.

7563613, Jul 21, 2009

Aug 1, 2005

11/195046

Donn M. Dennis - Gainesville FL, US
Charles R. Martin - Gainesville FL, US
Timothy E. Morey - Gainesville FL, US
Richard E. Partch - Potsdam NY, US
Dinesh O Shah - Gainesville FL, US
Manoj Varshney - Gainesville FL, US

University of Florida - Gainesville FL

C02F 3/34, A61K 9/14, A61K 38/43

435262, 424 941, 424489

A method of removing a toxic compound comprising contacting the toxic compound with a particle having two regions, the first region containing a detoxifying enzyme and the second region containing a material selected to partition the toxic compound into the second region. The particle may be a nanoparticle.

2004019, Oct 7, 2004

Oct 6, 2003

10/679581

Donn Dennis - Gainesville FL, US
Nikolaus Gravenstein - Gainesville FL, US
Jerome Modell - Gainesville FL, US
Timothy Morey - Gainesville FL, US
Dinesh Shah - Gainesville FL, US

University of Florida Research Foundation, Incorporated

A61K031/30

514/499000

A microemulsion delivery system for water insoluble or sparingly water soluble drugs that comprises a long polymer chain surfactant component and a short fatty acid surfactant component, with the amount of each being selected to provide stable microemulsion or micellar systems.

7202282, Apr 10, 2007

Apr 22, 2003

10/420608

Donn M. Dennis - Gainesville FL, US
Timothy E. Morey - Gainesville FL, US
Richard E. Partch - Hannawa Falls NY, US
Dinesh O. Shah - Gainesville FL, US
Manoj Varshney - Gainesville FL, US

University of Florida - Gainesville FL

B01F 3/08, A01N 43/40, A61K 31/445

516 53, 210643, 514330

The subject invention provides microemulsions having, as one component thereof, electron-deficient aromatic rings, e. g. di(trifluoromethyi) benzene, for efficient separation and/or isolation of target molecules, e. g. , bupivacaine.