THOMAS W SMITH
Gas Fitter in Weymouth, MA
License number
Massachusetts 2207
Type
Journeyman Gas Fitter
Address
Address
Weymouth, MA 02189
Personal information
See more information about THOMAS W SMITH at radaris.comName
Address
Phone
50 Apple Hill Dr, Tewksbury, MA 01876
50 Brooks Rd, Templeton, MA 01468
511 Concord St, Lowell, MA 01852
Professional information
Apyrase Polypeptides And Nucleic Acids Encoding Same
US Patent:
2006005, Mar 9, 2006
Filed:
Dec 12, 2002
Appl. No.:
10/498691
Inventors:
Thomas Smith - Weymouth MA, US
Terence Kirley - Cincinnati OH, US
Terence Kirley - Cincinnati OH, US
International Classification:
C12N 9/02, C07H 21/04, C12P 21/06
US Classification:
435189000, 435069100, 435320100, 435325000, 536023200
Abstract:
The present invention provides novel isolated polynucleotides encoding a novel extracellular nucleotidase, which belngs to a new family of calcium dependent apyrases. Also provided are antibodies that immunospecifically bind to the apyrase polypeptide or any derivative (including fusion derivative), variant, mutant or fragment of the novel polypeptide, polynucleotide or antibody. The invention additionally provides methods in which the apyrase polypeptide, polynucleotide and antibody are utilized in the treatment of vascular disorders, including disorders characterized by platelet aggregation.