Thomas R Wilson
Engineers in Fort Collins, CO
License number
Colorado 67276
Issued Date
Oct 20, 2011
Renew Date
Oct 20, 2011
Type
Engineer Intern
Address
Address
327 Remington B11, Fort Collins, CO 80521
Professional information
Recombinant Bhlh-Pas/Jhr Polypeptide And Its Use To Screen Potential Insecticides
US Patent:
6326165, Dec 4, 2001
Filed:
Nov 17, 1997
Appl. No.:
8/971188
Inventors:
Thomas G. Wilson - Fort Collins CO
Julia N. Heinrich - Princeton NJ
Julia N. Heinrich - Princeton NJ
Assignee:
Colorado State University Research Foundation - Fort Collins CO
American Cyanamid Company - Princeton NJ
American Cyanamid Company - Princeton NJ
International Classification:
C12P 2100, C12P 2102, C12N 1563, C12N 510
US Classification:
435 691
Abstract:
Promising groups of environmentally-safe insecticides consist of analogues of insect hormones, such as juvenile hormone, and antagonists of such hormones. The traditional bioassay approach for screening potential juvenile hormone analogs and antagonists is slow, expensive and inefficient. A recombinant bHLH-PAS-juvenile hormone receptor, isolated from methoprene-tolerant locus on Drosophila, provides the basis of in vitro and in vivo binding assays that can be used to discover new juvenile hormone-type targeted insecticides. Moreover, the nucleotide sequence of the Drosophila bHLH-PAS/JHR polypeptide provides tools for isolating juvenile hormone receptor genes from other insect species.