THOMAS R RYAN
Landscape Architect in Waltham, MA

License number
Massachusetts 590
Issued Date
Oct 20, 1978
Expiration Date
Jan 31, 2017
Type
Landscape Architect
Address
Address
Waltham, MA 02453

Professional information

Thomas Ryan Photo 1

System And Method For Reshaping An Eye Feature

US Patent:
8348935, Jan 8, 2013
Filed:
Sep 11, 2008
Appl. No.:
12/209123
Inventors:
David Muller - Boston MA, US
Ronald Scharf - Waltham MA, US
Thomas Ryan - Waltham MA, US
Neal Marshall - Ashby MA, US
Artie Wu - Boston MA, US
Assignee:
Avedro, Inc. - Waltham MA
International Classification:
A61B 18/14
US Classification:
606 34, 606 41
Abstract:
A system for applying therapy to an eye includes an applicator having a conducting element configured to direct energy from an energy source to an application end of the conducting element, where the application end has at least one eye contact portion. A positioning system positions the at least one eye contact portion in stable engagement with the eye surface. The conducting element is disposed within a housing for the applicator and at least one adjustment system is employed to move the conducting element relative to the housing. The at least one adjustment system enables controlled movement of the conducting element and the at least one eye contact portion against the corneal surface. In particular embodiments, sufficient contact between the applicator and the cornea is determined by causing applanation of the cornea. In other embodiments, at least one measurement device is employed to determine when sufficient contact has been established.


Thomas Ryan Photo 2

Windowed Thermal Ablation Probe

US Patent:
2010022, Sep 2, 2010
Filed:
Dec 21, 2009
Appl. No.:
12/643997
Inventors:
Jeffrey Sutton - Medway MA, US
Thomas Ryan - Waltham MA, US
Samit Patel - San Francisco CA, US
Richard Pellegrino - Half Moon Bay CA, US
Assignee:
RELIEVANT MEDSYSTEMS, INC. - Redwood City CA
International Classification:
A61B 18/14
US Classification:
606 41
Abstract:
A method and apparatus for treating an intraosseous nerve. The method includes positioning a hollow shaft through the cortical shell of a vertebral body and into a cancellous bone region of the vertebral body. The hollow shaft includes an annular wall having a longitudinal bore therein, a proximal portion and a distal portion, and a first window extending transversely through the annular wall. An electrosurgical probe is advanced within the longitudinal bore from the proximal portion toward the distal portion. The electrosurgical probe includes a first treatment element at a distal end of the probe, wherein the first treatment element being in electrical connection with a power supply. The first treatment element is slidably disposed within the longitudinal bore so that the first treatment element is advanced radially outward from the window and shaft to affect treatment of the intraosseous nerve within the cancellous bone region.


Thomas Ryan Photo 3

Eye Therapy System

US Patent:
2010025, Oct 7, 2010
Filed:
Apr 2, 2010
Appl. No.:
12/753465
Inventors:
David Muller - Boston MA, US
Thomas Ryan - Waltham MA, US
Ronald Scharf - Waltham MA, US
Assignee:
Avedro, Inc. - Waltham MA
International Classification:
A61B 18/18, A61N 1/00
US Classification:
606 34, 607 53
Abstract:
Embodiments according to aspects of the present invention provide a single convenient and versatile tool that allows an operator to apply energy to the cornea according to different patterns to suit different treatment cases, without requiring multiple applicators or interchangeable components. An electrical energy applicator in one embodiment extends from a proximal end to a distal end. The energy conducting applicator includes, at the proximal end, a connection to one or more electrical energy sources. The energy conducting applicator directs electrical energy from the one or more electrical energy sources to the distal end. The distal end is positionable at a surface of an eye. The energy conducting applicator includes at least three selectable conductors coupled to the one or more electrical energy sources. The selectable conductors define an outer conductor and an inner conductor being separated by a gap. Each of the selectable conductors are independently activated or deactivated according to a pattern of electrical energy to be applied to the eye.


Thomas Ryan Photo 4

Eye Therapy System

US Patent:
8545487, Oct 1, 2013
Filed:
Dec 5, 2008
Appl. No.:
12/315829
Inventors:
David Muller - Boston MA, US
Thomas Ryan - Waltham MA, US
Assignee:
Avedro Inc. - Waltham MA
International Classification:
A61B 17/22
US Classification:
606 5, 128898
Abstract:
Heat is generated in corneal fibrils in a cornea of an eye according to a selected pattern. The heat causes the corneal fibrils corresponding to the selected pattern to transition from a first structure to a second structure. The second structure provides a desired reshaping of the cornea. A cross-linking agent is then activated in the region of corneal fibrils according to the selected pattern. The cross-linking agent prevents the corneal fibrils from changing from the second structure. Thus, embodiments stabilize corneal tissue and improve its biomechanical strength after desired structural changes have been achieved in the corneal tissue. Accordingly, the embodiments help to preserve the desired reshaping of the cornea.


Thomas Ryan Photo 5

Eye Therapy System

US Patent:
2014002, Jan 23, 2014
Filed:
Sep 24, 2013
Appl. No.:
14/035477
Inventors:
Thomas Ryan - Waltham MA, US
Assignee:
Avedro, Inc. - Waltham MA
International Classification:
A61F 9/007
US Classification:
606 5
Abstract:
Heat is generated in corneal fibrils in a cornea of an eye according to a selected pattern. The heat causes the corneal fibrils corresponding to the selected pattern to transition from a first structure to a second structure. The second structure provides a desired reshaping of the cornea. A cross-linking agent is then activated in the region of corneal fibrils according to the selected pattern. The cross-linking agent prevents the corneal fibrils from changing from the second structure. Thus, embodiments stabilize corneal tissue and improve its biomechanical strength after desired structural changes have been achieved in the corneal tissue. Accordingly, the embodiments help to preserve the desired reshaping of the cornea.


Thomas Ryan Photo 6

Eye Therapy System

US Patent:
2010028, Nov 4, 2010
Filed:
Apr 2, 2010
Appl. No.:
12/753662
Inventors:
David Muller - Boston MA, US
Neal Marshall - Ashby MA, US
Thomas Ryan - Waltham MA, US
Assignee:
Avedro, Inc. - Waltham MA
International Classification:
A61B 18/18
US Classification:
606 33
Abstract:
An electrical energy applicator directs electrical energy from the electrical energy source to a distal end, which positionable at a surface of an eye. The energy conducting applicator includes a first conductor and a second conductor separated by a gap. The first conductor has a first contact surface at the distal end, and the second conductor has a second contact surface at the distal end. The first conductor and/or the second conductor has a length that is adjustable by a biasing element. The first contact surface of the first conductor is movable relative to the second contact surface of the second conductor. The first contact surface and the second contact surface are adjustably positionable simultaneously against the surface of the eye to deliver energy to the eye according to a pattern defined by the first contact surface, the second contact surface, and the gap.


Thomas Ryan Photo 7

Eye Therapy System

US Patent:
2010025, Oct 7, 2010
Filed:
Apr 2, 2010
Appl. No.:
12/753523
Inventors:
David Muller - Boston MA, US
Thomas Ryan - Waltham MA, US
Ronald Scharf - Waltham MA, US
Assignee:
Avedro, Inc. - Waltham MA
International Classification:
A61N 1/00, A61F 9/007
US Classification:
607 53
Abstract:
An electrical energy applicator in one embodiment extends from a proximal end to a distal end. The energy conducting applicator includes, at the proximal end, a connection to one or more electrical energy sources. The energy conducting applicator directs electrical energy from the one or more electrical energy sources to the distal end. The energy conducting applicator includes an outer conductor and an inner conductor extending to the distal end. The outer conductor and the inner conductor are separated by a gap. The outer conductor includes a plurality of moveable outer segments and the inner conductor includes a plurality of moveable inner segments. The plurality of outer segments and the plurality of inner segments form a total contact surface at the distal end. The total contact surface is positionable at a surface of an eye. The electrical energy is applied to the eye according to the total contact surface.


Thomas Ryan Photo 8

Eye Therapy System

US Patent:
8202272, Jun 19, 2012
Filed:
Sep 11, 2008
Appl. No.:
12/208963
Inventors:
David Muller - Boston MA, US
Ronald Scharf - Waltham MA, US
Thomas Ryan - Waltham MA, US
Neal Marshall - Ashby MA, US
Radha Pertaub - Somerville MA, US
Artie Wu - Boston MA, US
Assignee:
Avedro, Inc. - Waltham MA
International Classification:
A61B 18/18
US Classification:
606 41
Abstract:
A system for applying therapy to an eye selectively applies coolant to the corneal surface to minimize heat-related damage to the corneal surface during thermokeratoplasty. Embodiments may include an energy source, a conducting element, a coolant supply, and a coolant delivery system. The conducting element is operably connected to the energy source and extends from a proximal end to a distal end. The conducting element directs energy from the energy source to the distal end, which is positionable at the eye. The coolant delivery system is in communication with the coolant supply and is operable to deliver a micro-controlled pulse of coolant to the distal end.


Thomas Ryan Photo 9

Eye Therapy System

US Patent:
2010018, Jul 22, 2010
Filed:
Nov 12, 2009
Appl. No.:
12/617554
Inventors:
David Muller - Boston MA, US
Radha Pertaub - Somerville MA, US
Steven Meyers - Waltham MA, US
Russ Dresher - Marlborough MA, US
Thomas Ryan - Waltham MA, US
Ronald Scharf - Waltham MA, US
Assignee:
AVEDRO, INC. - Waltham MA
International Classification:
A61B 18/08
US Classification:
606 33
Abstract:
Systems and methods improve operation of an applicator that delivers heat-generating energy to an eye as a part of an eye therapy. For example, reflected power may be measured to determine whether sufficient contact has been established between the applicator and the eye for accurate and precise delivery of energy to the eye. In addition, at least one of forward and reflected power may be measured to monitor the application of coolant pulses that control the generation of heat in the eye when the applicator delivers energy to the eye. Further, the forward and reflected power may be measured to determine an efficiency of energy transfer or an impedance mismatch. Based on the efficiency of energy transfer or the impedance mismatch, an adjustable parameter of a tuning element may be modified.


Thomas Ryan Photo 10

Eye Therapy System

US Patent:
2013013, May 23, 2013
Filed:
May 14, 2012
Appl. No.:
13/470975
Inventors:
David Muller - Boston MA, US
Ronald Scharf - Waltham MA, US
Thomas Ryan - Waltham MA, US
Neal Marshall - Ashby MA, US
Radha Pertaub - Watertown MA, US
Artie Wu - Boston MA, US
Assignee:
Avedro, Inc. - Waltham MA
International Classification:
A61F 9/007
US Classification:
606 41
Abstract:
A system for applying therapy to an eye selectively applies coolant to the corneal surface to minimize heat-related damage to the corneal surface during thermokeratoplasty. Embodiments may include an energy source, a conducting element, a coolant supply, and a coolant delivery system. The conducting element is operably connected to the energy source and extends from a proximal end to a distal end. The conducting element directs energy from the energy source to the distal end, which is positionable at the eye. The coolant delivery system is in communication with the coolant supply and is operable to deliver a micro-controlled pulse of coolant to the distal end.