THOMAS P FARRELL
Engineers in Warrington, PA

6420473, Jul 16, 2002

Feb 10, 2000

09/501866

Ramireddy Chittamuru - Lansdale PA
George Reyes - Perkiomenville PA
Thomas P. Farrell - Warrington PA
Charles F. Vesey - Hatfield PA
Dev K. Mehra - Furlong PA
Hans-Ulrich Petereit - Darmstadt, DE
Klaus Lehmann - Rossdorf, DE

BPSI Holdings, Inc. - Wilmington DE

C08J 312

524447, 424 33, 424 34

A non-toxic, edible, enteric film coating, dry powder composition for use in making an aqueous enteric suspension which may be used in coating pharmaceutical tablets comprises a) an acrylic resin, said resin comprising i) from 20 to 85 percent by weight of at least one alkyl acrylate or alkyl methacrylate moiety, ii) from 80 to 15 percent by weight of at least one vinyl or vinylidene moiety having a carboxylic acid group capable of salt formation, and iii) from 0 to 30 percent by weight of at least one other vinyl or vinylidene moiety copolymerizable with i) and ii), b) an alkalizing agent capable of reacting with the acrylic resin such that, after reaction, 0. 1 to 10 mole percent of the acidic groups in 1a-ii) are present in the salt form, and c) a detackifier.

2006022, Oct 12, 2006

Jun 10, 2004

10/560368

Frederick Kettinger - Norristown PA, US
Charles Fields - Kent, GB
Thomas Farrell - Warrington PA, US

G06K 19/00

235487000

Oral solid dosage forms such as tablets having overt, printed or etched markings as well as optional covert markings are disclosed. The markings can be rapidly identified to authenticate a dosage form and/or drug contained therein. The inventive dosage forms include a core portion having sufficiently low friability to receive a printed or etched marking on a surface thereof, and a readable or detectable printed or etched marking on the surface of the core which provides information allowing the identification/authentication of the oral dosage form. In preferred aspects of this embodiment, a bar code, more preferably, a 2D data matrix bar code is printed or etched on a debossed region on the surface of the solid dose form. Methods of preparing the marked dosage forms and methods of identifying and/or authenticating solid dosage forms are also disclosed.

8647645, Feb 11, 2014

Apr 28, 2010

12/769188

Thomas P. Farrell - Warrington PA, US
Jason Teckoe - Lansdale PA, US

BPSI Holdings, LLC - Wilmington DE

A61K 47/10

424400, 424463, 424474, 424475, 424482, 424490, 424497

The present invention is directed to immediate release film coating systems for use on oral dosage forms such as compressed tablets and other orally-ingestible substrates which have improved moisture barrier properties. The film coating systems can be applied either directly to a substrate or after the substrate has been coated with a subcoat. In preferred aspects, the moisture barrier film coating is prepared as a dry powder mixture containing polyvinyl alcohol, a polymer with pH dependent solubility, a plasticizer, a glidant, and, optionally, a detackifier, an alkalizing agent and a pigment. Film coating compositions containing an aqueous suspension of the powder mixtures, methods of applying the coatings to substrates and the coated substrates are also disclosed.

2006025, Nov 9, 2006

May 6, 2004

10/554677

Thomas Farrell - Warrington PA, US
Kurt Fegely - Limerick PA, US
Christopher Young - Austin TX, US
Michael Crowley - Austin TX, US
James McGinity - Austin TX, US

A61K 9/14, C08L 33/04

424487000, 525222000

Thermoformed or hot melt extruded pharmaceutical compositions containing an active pharmaceutical ingredient, acrylic enteric polymer and plasticizer are disclosed. Methods of making the same as well as various pharmaceutical dosage forms are also disclosed. In preferred aspects, a thermoformable mixture is in a powder form and includes an active ingredient, plasticizer, acrylic polymer and optional excipients which enhance the performance of the extrudate after being incorporated into a dosage form.

8388983, Mar 5, 2013

Apr 28, 2010

12/769197

Thomas P. Farrell - Warrington PA, US
Jason Teckoe - Lansdale PA, US
Barry Friend - Dartford, GB
Scott Gulian - Lansdale PA, US

BPSI Holdings, LLC - Wilmington DE

A61K 47/32, A61K 9/00, B05D 7/00, C08K 5/41

424400, 427 214, 524156, 5147726

The present invention is directed to film coating compositions for use on oral dosage forms such as compressed tablets and other orally-ingestible substrates which contain a fine particle size detackifier. The film coating compositions can be applied either directly to a substrate or after the substrate has been coated with a subcoat. In preferred aspects, the polymer is either polyvinyl alcohol or a copolymer of polyvinyl alcohol. Aqueous suspensions comprising the inventive film coating compositions, methods of applying the coatings to substrates and the coated substrates themselves are also disclosed.

6902609, Jun 7, 2005

Feb 13, 2004

10/778600

Rita M. Steffenino - Green Lane PA, US
Franklin J. Gulian - Schwenksville PA, US
Irvin M. Lash - Pennsburg PA, US
Thomas P. Farrell - Warrington PA, US
Charles D. Fields - West Mailing, GB

BPSI Holdings, Inc. - Wilmington DE

C09D005/36, C09D101/00, C09D101/26, C09D101/28, C09D105/00

1061628, 1061629, 424476, 424480, 427 223, 427415, 426103, 426302, 426303, 426304

The present invention is directed to film coating systems for use on oral dosage forms such as compressed tablets and orally-ingestible substrates which have improved pearlescent qualities. The film coating systems can be applied either directly to a substrate or after the substrate has been coated with a subcoat. In preferred aspects, the pearlescent film coating is prepared as a dry powder mixture containing a cellulosic polymer, a detackifier, a gloss enhancer, and a pearlescent pigment. Film coating compositions containing an aqueous suspension of the powder mixtures, methods of applying the coatings to substrates and the coated substrates are also disclosed.

2001002, Sep 20, 2001

Jan 19, 2001

09/766859

Ramireddy Chittamuru - Lansdale PA, US
George Reyes - Perkiomenville PA, US
Thomas Farrell - Warrington PA, US
Charles Vesey - Hatfield PA, US
Dev Mehra - Furlong PA, US
Hans-Ulrich Petereit - Darmstadt, DE
Klaus Lehmann - Rossdorf, DE

A61K047/00

424/439000, 427/002210, 424/440000, 424/476000, 424/479000, 424/480000, 424/481000, 424/482000, 424/490000, 424/493000, 424/494000, 424/496000, 424/497000, 424/498000, 524/089000, 524/297000

A non-toxic, edible, enteric film coating, dry powder composition for use in making an aqueous enteric suspension which may be used in coating pharmaceutical tablets comprises a) an acrylic resin, said resin comprising i) from 20 to 85 percent by weight of at least one alkyl acrylate or alkyl methacrylate moiety, ii) from 80 to 15 percent by weight of at least one vinyl or vinylidene moiety having a carboxylic acid group capable of salt formation, and iii) from 0 to 30 percent by weight of at least one other vinyl or vinylidene moiety copolymerizable with i) and ii), b) an alkalizing agent capable of reacting with the acrylic resin such that, after reaction, 0.1 to 10 mole percent of the acidic groups in 1a-ii) are present in the salt form, and c) a detacktifier.

2006013, Jun 22, 2006

Dec 16, 2005

11/305900

Thomas Farrell - Warrington PA, US
Kurt Fegely - Gilbertsville PA, US
George Reyes - Perkiomenville PA, US
Budhi Simon - Harleysville PA, US
Cara Young - Blue Bell PA, US

A61K 9/24

424472000

Dry, enteric, film-coating compositions and aqueous dispersions containing the same are disclosed. When applied to orally-ingestible substrates such as oral solid dosage forms, the film coatings are capable of preventing the substrates from disintegrating in media with pH values from about 1 to about 4.5 or higher values. One preferred film-coating composition contains a micronized intermediate comprised of an acrylic resin and talc. Advantageously and surprisingly, the preferred film-coating composition does not contain an alkalizing agent.