Inventors:
Thomas NAJARIAN - Los Osos CA, US
Kathyrn Susan UNKEL - Los Osos CA, US
International Classification:
A61K 31/439, A61K 31/4178, A61K 31/557, A61P 15/00, A61P 35/00, A61P 13/02
Abstract:
Methods of treating disorders with cholinergic agonists for example, muscarinic receptor agonists such as pilocarpine and cevimeline are provided. In particular, methods of treating and/or preventing interstitial cystitis, yeast infections, urinary tract infections, atrophic vaginitis, vaginal dryness, and sexual dysfunction associated with vaginal dryness by administering a cholinergic agonist to the subject suffering from the disorders are provided. In addition, intra-vaginal administration of cholinergic agonists such as muscarinic receptor agonists to patients suffering from interstitial cystitis, vaginal dryness, and sexual dysfunction associated with vaginal dryness is also provided.