Inventors:
Murty Arimilli - Fremont CA, US
Daphne Kelly - San Francisco CA, US
Thomas Lee - Redwood City CA, US
Lawrence Manes - Moss Beach CA, US
John Munger - Alviso CA, US
Ernest Prisbe - Los Altos CA, US
Lisa Schultze - San Carlos CA, US
International Classification:
A61K031/675, C07F009/6512
Abstract:
The invention provides crystalline forms of adefovir dipivoxil and methods to prepare the crystals. The compositions and methods of the present invention have desirable properties for large scale synthesis of crystalline adefovir dipivoxil or for its formulation into therapeutic dosages. Invention compositions include an anhydrous crystal form of adefovir dipivoxil.