Inventors:
Thomas Guttuso - Snyder NY, US
Assignee:
UNIVERSITY OF ROCHESTER - Rochester NY
International Classification:
A61K 31/195, A61K 31/196, A61P 1/00, A61P 25/00, A61P 25/06, A61P 25/22, A61P 25/30
Abstract:
A method of treating a patient for a condition characterized by symptoms that can be alleviated by interfering with or supplementing the activity of endogenous ligands on the αδ subunit of a voltage gated calcium channel, said method comprising: administering to a patient experiencing the condition an amount of one or more of L-norleucine, L-isoleucine, L-alloisoleucine, L-methionine, L-leucine, 2-cyclohexylglycine, 2-phenylglycine, 2-amino-2-norbornane carboxylic acid, 1-aminocyclohexane carboxylic acid, 2-aminoheptanoic acid, 2-aminocaprylic acid, and 2-aminononanoic acid under conditions effective to treat the condition.