MR. THOMAS FRANCIS GREENE, FNP
Nursing at Madison St, Seattle, WA
License number
Washington AP60389431
Category
Nursing
Type
Family
Address
Address
2
1101 Madison St SUITE 900, Seattle, WA 98104
PO Box 25608, Salt Lake City, UT 84125
PO Box 25608, Salt Lake City, UT 84125
Phone
(206) 215-6800
(206) 215-6801 (Fax)
(206) 320-4476
(206) 568-7043 (Fax)
(206) 215-6801 (Fax)
(206) 320-4476
(206) 568-7043 (Fax)
Personal information
See more information about THOMAS FRANCIS GREENE at radaris.comName
Address
Phone
5356 Ruby Pl NE, Seattle, WA 98110
Professional information
Thomas Greene - Salt Lake City, UT
Work:
Utah Medical Insurance Company
Senior Investigator St. Paul Insurance Co - Salt Lake City, UT
Senior Liability Administrator American Stores Co - Salt Lake City, UT
Senior Liability Administrator
Senior Investigator St. Paul Insurance Co - Salt Lake City, UT
Senior Liability Administrator American Stores Co - Salt Lake City, UT
Senior Liability Administrator
Education:
University of Utah - Salt Lake City, UT
Bachelor of Science
Bachelor of Science
Sales Mgr At Interpack Nw Frozen Foods Inc.
Position:
Sales Mgr at Interpack NW Frozen Foods Inc.
Location:
Greater Seattle Area
Industry:
Food & Beverages
Work:
Interpack NW Frozen Foods Inc.
-
Sales Mgr
Thomas Francis Greene, Seattle WA
Specialties:
Family Nurse Practitioner
Address:
1101 Madison St, Seattle, WA 98104
11522 Ne 20Th St, Bellevue, WA 98004
11522 Ne 20Th St, Bellevue, WA 98004
Detection And Quantitation Of 8-Oh-Adenine Using Monoclonal Antibodies
US Patent:
6900291, May 31, 2005
Filed:
Feb 25, 2003
Appl. No.:
10/375697
Inventors:
Eric H. Holmes - Bothell WA, US
Thomas G. Greene - Seattle WA, US
Thomas G. Greene - Seattle WA, US
Assignee:
CytoChem, Inc. - Seattle WA
International Classification:
C12Q001/68
US Classification:
5303871, 530350, 530403, 5303881, 4241931, 435 6, 435 5, 435 72, 435 71, 435 791, 435 792
Abstract:
The present invention relates to methods and materials for the detection and quantitation 8-OH-Ade in biological specimens. Specifically, the present invention is directed to a group of highly specific monoclonal antibodies reactive with the modified nucleoside structure 8-OH-Ade, and to various immunoassays for 8-OH-Ade utilizing these monoclonal antibodies. The monoclonal antibodies of the present invention may be used in assays for diagnosing or monitoring the progression of certain types of cancer, in addition to a variety of other diseases associated with mutagenesis resulting from oxidative damage of DNA. Assays utilizing the monoclonal antibodies of the present invention may also be used to analyze or monitor toxicant exposure, such as from environmental sources. The monoclonal antibodies of the present invention were prepared with the immunogen 8-OH-adenosine coupled to keyhole limpet hemocyanin (KLH), not to 8-OH-Ade directly. It is believed that the monoclonal antibodies bind with the base portion of the structure (8-OH-Ade) and not the carbohydrate (ribose) or protein linkage region of the conjugate, because, as demonstrated, conjugates bound to nucleosides other than 8-OH-adenosine were unreactive with these antibodies.
Detection And Quantitation Of 8-Oh-Adenine Using Monoclonal Antibodies
US Patent:
6187551, Feb 13, 2001
Filed:
Mar 18, 1998
Appl. No.:
9/043461
Inventors:
Eric H. Holmes - Bothell WA
Thomas G. Greene - Seattle WA
Thomas G. Greene - Seattle WA
Assignee:
CytoChem, Inc. - Seattle WA
International Classification:
G01N 3353
US Classification:
435 792
Abstract:
The present invention relates generally to assays for 8-hydroxyadenine (8-OH-Ade) and, more particularly, to improved immunoassays for the detection and quantitation of 8-OH-Ade in biological specimens. The present invention further relates to new monoclonal antibodies directed against 8-OH-Ade for use in the immunoassays.