Inventors:
Alexander Pines - Berkeley CA, US
Thomas Budinger - Berkeley CA, US
Gil Navon - Ramat Gan, IL
Stephan Appelt - Waiblingen, DE
Angelo Bifone - Rome, IT
Rebecca Taylor - Berkeley CA, US
Boyd Goodson - Berkeley CA, US
Roberto Seydoux - Berkeley CA, US
Toomas Room - Albany CA, US
Tanja Pietrass - Socorro NM, US
Assignee:
Lawrence Berkeley National Laboratory - Berkeley CA
International Classification:
G01V 3/00, G01N 24/00, A61B 5/055
US Classification:
324301, 324307, 436173, 424 93
Abstract:
The present invention relates generally to nuclear magnetic resonance (NMR) techniques for both spectroscopy and imaging. More particularly, the present invention relates to methods in which hyperpolarized noble gases (e. g. , Xe and He) are used to enhance and improve NMR and MRI. Additionally, the hyperpolarized gas solutions of the invention are useful both in vitro and in vivo to study the dynamics or structure of a system. When used with biological systems, either in vivo or in vitro, it is within the scope of the invention to target the hyperpolarized gas and deliver it to specific regions within the system.