THOMAS EDWARD ZEWERT
Medical Practice in Pittsburgh, PA
License number
Pennsylvania MD070307L
Category
Medicine
Type
Medical Physician and Surgeon
Address
Address
Pittsburgh, PA 15206
Personal information
See more information about THOMAS EDWARD ZEWERT at radaris.comName
Address
Phone
28 Jericho Run, Wshngtn Xing, PA 18977
962 West St, Washington Crossing, PA 18977
413 Gettysburg St, Pittsburgh, PA 15206
2034 Swallow Hill Rd, Pittsburgh, PA 15220
Professional information
Biopotential Measurement Including Electroporation Of Tissue Surface
US Patent:
6085115, Jul 4, 2000
Filed:
May 22, 1998
Appl. No.:
9/083497
Inventors:
James C. Weaver - Sudbury MA
Uwe Pliquett - Grossdornberg, DE
Rita Vanbever - Brussels, BE
Thiruvallur R. Gowrishankar - Waltham MA
Thomas E. Zewert - Pittsburgh PA
Uwe Pliquett - Grossdornberg, DE
Rita Vanbever - Brussels, BE
Thiruvallur R. Gowrishankar - Waltham MA
Thomas E. Zewert - Pittsburgh PA
Assignee:
Massachusetts Institite of Technology - Cambridge MA
International Classification:
A61B 504
US Classification:
600509
Abstract:
A method for measuring biopotential of an organism includes electroporating a portion of a tissue surface of the organism. The biopotential of the organism is then measured with electrodes at the electroporated portion of the organism. The portion of the organism that is electroporated can be, for example, a skin surface of the organism. A resistance-decreasing agent, such as heparin, sodium thiosulfate, thioglycolic acid solution and dithioglycolic acid can be applied to the tissue surface to facilitate reduction in electrical resistance. Another example of a resistance-decreasing agent is a keratin-disrupting agent, such as sulforhodamine. Examples of suitable biopotential measurements include electrocardiographic, electroencephalographic, electromyographic, electrohysterographic and elctrokymographic measurements. The method decreases skin resistance to diminish unwanted electrical voltages that compete with biopotential measurements, thereby significantly improving the biopotential measurement.