THOMAS CARR WRIGHT, M.D.
Medical Practice at Station Rd, Irvington On Hudson, NY

5814448, Sep 29, 1998

Jan 31, 1996

8/594600

Saul J. Silverstein - Irvington NY
Octavian Lungu - New York NY
Thomas C. Wright - Irvington NY

The Trustees of Columbia University in the City of New York - New York NY

C12Q 168, C12P 1934, C07H 2104

435 6

This invention provides a method of typing a human papillomavirus in a patient infected by human papillomavirus which comprises: obtaining a sample containing DNA from the human papillomavirus to be typed; amplifying the L1 portion of the human papillomavirus DNA; treating the resulting amplified DNA with a plurality of predetermined restriction enzymes so as to produce restriction fragments; and analyzing the fragments so produces so as to type the human papillomavirus.

5888724, Mar 30, 1999

Jun 7, 1995

8/479777

Saul J. Silverstein - Irvington NY
Octavian Lungu - New York NY
Thomas C. Wright - Irvington NY
Ralph M. Richart - Oakdale NY

The Trustees of Columbia University in the City of New York - New York NY

C12Q 170, C12Q 168, C12P 1934

435 5

This invention provides a method of detecting a high oncogenic-risk type human papillomavirus in a subject which comprises: obtaining from a subject a specimen containing cervical cells and treating the specimen so as to recover nucleic acid molecules present in the cervical cells; contacting the resulting nucleic acid molecules with multiple pairs of single-stranded labeled oligonucleotide primers capable of specifically hybridizing with a different high oncogenic-risk type of human papillomavirus; amplifying any nucleic acid molecules to which a pair of primers hybridizes so as to obtain a double-stranded amplification product and treating any double-stranded amplification product so as to obtain single-stranded nucleic acid molecules; contacting any resulting single-stranded nucleic acid molecules with multiple single-stranded labeled oligonucleotide probes which are capable of specifically hybridizing with such high oncogenic-risk types of human papillomavirus; contacting any resulting hybrids with a marked antibody capable of specifically forming a complex with the labeled probe, when the probe is present in such a complex; and detecting the presence of any resulting complexes, the presence thereof being indicative of the presence of a high oncogenic-risk type human papillomavirus in the initial specimen.

5543294, Aug 6, 1996

Jun 8, 1994

8/255561

Saul J. Silverstein - Irvington NY
Octavian Lungu - New York NY
Thomas C. Wright - Irvington NY

The Trustees of Columbia University in the City of New York - New York NY

C12Q 168, C07H 2104

435 6

The subject invention provides a method of diagnosing congenital adrenal hyperplasia in a human subject. The subject invention also provides a method of typing a human papillomavirus in a patient infected by a human papillomavirus. The subject invention further provides a method for detecting Mycobacteria in a clinical sample. Finally, the subject invention provides a method for typing Mycobacteria in a clinical sample containing Mycobacteria.