THOMAS ALLAN BAILLIE
Pilots at 203 St, Seattle, WA
License number
Washington A2145502
Issued Date
Jul 2015
Expiration Date
Jul 2017
Category
Airmen
Type
Authorized Aircraft Instructor
Address
Address
4775 NE 203Rd St, Seattle, WA 98155
Professional information
Dean, School Of Pharmacy At University Of Washington
Position:
Dean, School of Pharmacy at University of Washington
Location:
Greater Seattle Area
Industry:
Higher Education
Work:
University of Washington
-
Dean, School of Pharmacy
Merck & Co
Oct 1994 - Aug 2008
-
Vice President, DMPK
Education:
University of Glasgow 1970 - 1973
PhD, Chemistry University of Glasgow 1966 - 1970
BSc, Chemistry
PhD, Chemistry University of Glasgow 1966 - 1970
BSc, Chemistry
Dean, School Of Pharmacy At University Of Washington
Location:
Greater Seattle Area
Industry:
Education Management
Biodegradable Lipids For The Delivery Of Active Agents
US Patent:
2012002, Feb 2, 2012
Filed:
Jun 3, 2011
Appl. No.:
13/153200
Inventors:
Muthiah MANOHARAN - Cambridge MA, US
Martin Maier - Cambridge MA, US
Muthusamy Jayaraman - Cambridge MA, US
Shigeo Matsuda - Cambridge MA, US
Akin Akinc - Cambridge MA, US
Thomas A. Baillie - Seattle WA, US
Martin Maier - Cambridge MA, US
Muthusamy Jayaraman - Cambridge MA, US
Shigeo Matsuda - Cambridge MA, US
Akin Akinc - Cambridge MA, US
Thomas A. Baillie - Seattle WA, US
Assignee:
ALNYLAM PHARMACEUTICALS, INC. - Cambridge MA
International Classification:
A61K 47/44, A61K 31/713, A61P 37/04, C12N 5/071, C12N 15/85, C07C 229/30, A61K 31/7088
US Classification:
4242831, 554110, 514785, 514 44 A, 514 44 R, 435375, 435455
Abstract:
The present invention relates to a cationic lipid having one or more biodegradable groups located in the mid- or distal section of a lipidic moiety (e.g., a hydrophobic chain) of the cationic lipid. These cationic lipids may be incorporated into a lipid particle for delivering an active agent, such as a nucleic acid. The invention also relates to lipid particles comprising a neutral lipid, a lipid capable of reducing aggregation, a cationic lipid of the present invention, and optionally, a sterol. The lipid particle may further include a therapeutic agent such as a nucleic acid.