THOMAS ALEXANDER OSBORNE
Pilots in Blmgtn, IN

5112308, May 12, 1992

Oct 3, 1990

7/592676

Douglas O. Olsen - Brentwood TN
Brian L. Bates - Bloomington IN
Thomas A. Osborne - Bloomington IN

Cook Incorporated - Bloomington IN

A61M 5178

604164

A medical device for endoscopic access of a body cavity and a method of percutaneously placing inner and outer access sheaths of the device into the body cavity. The medical device includes inner and outer access sheaths and a dilator which is inserted into the outer sheath and has a shoulder or a shoulder piece for abutting against the proximal end of the outer sheath. The device also includes a wire guide that is percutaneously inserted into the body cavity via an introducer needle. The dilator and outer sheath are placed over the wire guide to dilate the puncture site and introduce the dilator and outer sheath into the body cavity. The dilator comprises an elongated cylindrical member having a passageway opening distally from the conically-shaped distal end and from an outside lateral wall of the dilator about the proximal end. The dilator also includes an end cap which is utilized to force the dilator and the outer sheath through the puncture site and into the body cavity. After positioning in the body cavity, the dilator and wire guide are removed through the outer sheath.

4634433, Jan 6, 1987

May 6, 1985

6/731138

Thomas A. Osborne - Bloomington IN

Cook, Incorporated - Bloomington IN

A61M 2500

604171

A flexible sheath assembly for an indwelling catheter is provided which maintains the sterility of an otherwise exposed portion of an indwelling catheter so that the depth of insertion of the catheter within a body may be adjusted without causing contamination. The assembly includes a transparent flexible sheathing which is sealingly secured at its ends to front and rear hubs each having a passageway therethrough which is sized to permit passage of a catheter. The flexible sheathing is longitudinally expandable from a collapsed position wherein the sheathing is twisted about an axis substantially parallel to the length of the sheath. The flexible sheathing in the collapsed position defines a central passageway which is aligned with the front and rear hub passageways for permitting the catheter to be guided through the interior of the flexible sheathing as it is passed between the front and rear hubs. The central passageway is heat set in the flexible sheathing by placing the flexible sheath on a mandrel in its contracted position and heating the flexible sheath in an oven.

2010016, Jun 24, 2010

Dec 22, 2008

12/341459

William L. Howat - Laconia NH, US
Thomas A. Osborne - Bloomington IN, US

Cook Incorporated - Bloomington IN

A61M 5/00, B32B 37/06

60416401, 156 86

An introducer sheath includes a lubricious inner liner having a passageway extending longitudinally therethrough, a reinforcing member positioned over the inner liner, and an outer jacket positioned longitudinally over the reinforcing member and the inner liner. The outer jacket has a higher durometer proximal portion, a lower durometer distal portion, and a transition zone between the proximal portion and the distal portion. The transition zone has a variable durometer from a junction with the outer jacket proximal portion to a junction with the outer jacket distal portion, to provide a transition between the higher durometer proximal portion and the lower durometer distal portion.

2007024, Oct 18, 2007

Mar 26, 2007

11/728528

Dharmendra Pal - Wilmington MA, US
Thomas Osborne - Bloomington IN, US

Cook Incorporated - Bloomington IN

A61M 29/00, A61M 5/178, A61M 25/00

604164130, 604523000, 604104000

A catheter for use with at least two different sizes of wire guides is described. The catheter includes a wire guide lumen sized to receive a first wire guide of a first diameter. The catheter may also include a tip lumen that extends in a distal direction from a first opening in communication with the wire guide lumen to a second opening. The first opening is sized to receive the first wire guide, and the second opening is sized to receive a second wire guide of a smaller diameter than the first wire guide. The catheter also includes one or more longitudinal expansion features capable of radially expanding the tip lumen to receive a wire guide of a diameter up to the first diameter through the second opening. An adapter that may be attached to the catheter by a medical professional is also described.

2005018, Aug 25, 2005

Feb 9, 2005

11/054043

Scott Eells - Bloomington IN, US
Michael Hiles - Lafayette IN, US
Thomas Osborne - Bloomington IN, US

COOK INCORPORATED - Bloomington IN
COOK BIOTECH INC. - West Lafayette IN

A61F002/06

623001130, 623001470

A cast bioremodelable graft () comprising a cast tubular construct () of a bioremodelable substance (). The bioremodelable substance is cast on or applied to a form and then vacuum pressed to dry or harden the substance. Expandable members () are disposed on, in, under or about the cast tubular construct to expand the graft when released from an endoluminal delivery system. A second layer () can be applied over the first layer () and the expandable stents to contain the stents there between without the need for any separate attachment. The graft is dehydrated and preferably vacuum pressed to harden the bioremodelable substance. The form is removed to form one or more lumens (-) in the graft, which is then loaded on an endoluminal delivery system.

6200336, Mar 13, 2001

Jun 2, 1999

9/324382

Dusan Pavcnik - Portland OR
Frederick S. Keller - Portland OR
Josef Rosch - Portland OR
Thomas A. Osborne - Bloomington IN

Cook Incorporated - Bloomington IN

A61F 206

623 115

A multiple-sided medical device comprises a closed frame of a single piece of wire or other resilient material and having a series of bends and interconnecting sides. The device has both a flat configuration and a second, folded configuration that comprises a self-expanding stent. The stent is pushed from a delivery catheter into the lumen of a duct or vessel. One or more barbs are attached to the frame of the device for anchoring or to connect additional frames. A covering of fabric or other flexible material such as DACRON, PTFE, or collagen, is sutured or attached to the frame to form an occlusion device, a stent graft, or an artificial valve such as for correcting incompetent veins in the lower legs and feet. A partial, triangular-shaped covering over the lumen of the device allows the valve to open with normal blood flow and close to retrograde flow.

7563276, Jul 21, 2009

Oct 28, 2005

11/260981

Thomas A. Osborne - Bloomington IN, US
Charles W. Agnew - West Lafayette IN, US
Brian C. Case - Bloomington IN, US

Cook Incorporated - Bloomington IN

A61F 2/06

623 126, 623 214, 623 216

Prosthetic valves for regulating fluid flow through a body vessel are described. The valves include a valve member that includes at least a portion that is capable of moving to selectively permit and substantially prevent fluid flow through the body vessel, either alone or with one or more additional valve members. A cannula is associated with the valve and permits a controlled amount of fluid flow through the valve, such as retrograde flow while the valve member substantially prevents fluid flow through the body vessel.

2006020, Sep 7, 2006

Mar 2, 2006

11/366649

D. Lentz - Bloomington IN, US
Thomas Osborne - Bloomington IN, US

Cook Incorporated - Bloomington IN

A61M 25/00

604524000

An introducer sheath has an inner fluorocarbon liner, a reinforcing member disposed radially outwardly from the liner, and a polymeric intermediate layer positioned longitudinally over the reinforcing member and inner liner. A heat shrink layer formed of a block copolymer having cross-linked and non-cross-linked functional groups comprises an outer layer of the sheath. During for of the introducer sheath, the intermediate layer is melted and compressed in the heat shrink layer in a manner such that the inner surface of the intermediate layer bonds to the outer surface of the inner liner through spacings of the reinforcing member, and the outer surface of the intermediate layer bonds with non-cross-linked active functional groups of the heat shrink layer.

5601582, Feb 11, 1997

Nov 16, 1994

8/340565

Susan C. Shelton - Ararat NC
Neal E. Fearnot - West Lafayette IN
Thomas A. Osborne - Bloomington IN

Wilson-Cook Medical Inc. - Winston-Salem NC
MED Institute Inc. - W. Lafayette IN
Cook Inc. - Bloomington IN

A61B 1732, A61B 1720

606170

A papillotome (10) including a multi-lumen inner member tube (11) with an outer member tube (16) positioned around the proximal portion thereof with a spacing therebetween for limiting the radial expansion of the inner member tube so that the elastic limit of the inner member tube is not exceeded. The material of and the spacing between the inner and outer member tubes is selected so as to longitudinally distribute the radial expansion of the inner member tube from a fixed or partial attachment of the inner and outer member tubes.

RE31855, Mar 26, 1985

Nov 22, 1982

6/443321

Thomas A. Osborne - Bloomington IN

Cook, Inc. - Bloomington IN

A61M 2500

604161

This invention relates to a flexible cannula comprising material which tears readily in a longitudinal direction and can thus be easily removed by pulling tabs on opposite sides of the cannula apart after the catheter or other device has been inserted into the body.