THEODORE OTTO JOHNSON
Pilots at Torrey Vw Ct, San Diego, CA
License number
California A2257043
Category
Airmen
Type
Authorized Aircraft Instructor
Address
Address
3612 Torrey Vw Ct, San Diego, CA 92130
Professional information
Airlines/Aviation Professional
Location:
Greater San Diego Area
Antipicornaviral Compounds And Compositions, Their Pharmaceutical Uses, And Materials For Their Synthesis
US Patent:
6610730, Aug 26, 2003
Filed:
Apr 12, 2001
Appl. No.:
09/834783
Inventors:
Theodore O. Johnson Jr. - San Diego CA
Ye Hua - La Jolla CA
Hiep T. Luu - San Diego CA
Peter S. Dragovich - Encinitas CA
Ye Hua - La Jolla CA
Hiep T. Luu - San Diego CA
Peter S. Dragovich - Encinitas CA
Assignee:
Agouron Pharmaceuticals, Inc. - San Diego CA
International Classification:
C07D20704
US Classification:
514422, 548530, 548537, 548543, 548550, 548551, 548518
Abstract:
Compounds of the formula: where the formula variables are as defined in the disclosure, advantageously inhibit or block the biological activity of the picornaviral 3C protease. These compounds, as well as pharmaceutical compositions containing these compounds, are useful for treating patients or hosts infected with one or more picornaviruses, such as RVP. Intermediates and synthetic methods for preparing such compounds are also described.
Indazole Compounds And Pharmaceutical Compositions For Inhibiting Protein Kinases, And Methods For Their Use
US Patent:
2004017, Sep 2, 2004
Filed:
Feb 13, 2003
Appl. No.:
10/326755
Inventors:
Robert Kania - San Diego CA, US
Steven Bender - Oceanside CA, US
Allen Borchardt - San Diego CA, US
Stephan Cripps - San Diego CA, US
Ye Hua - La Jolla CA, US
Michael Johnson - San Diego CA, US
Theodore Johnson - San Diego CA, US
Hiep Luu - San Diego CA, US
Cynthia Palmer - San Diego CA, US
Siegfried Reich - Solana Beach CA, US
Min Teng - San Diego CA, US
Christine Thomas - West Borough MA, US
Michael Varney - Solana Beach CA, US
Michael Wallace - San Diego CA, US
Michael Collins - San Diego CA, US
Steven Bender - Oceanside CA, US
Allen Borchardt - San Diego CA, US
Stephan Cripps - San Diego CA, US
Ye Hua - La Jolla CA, US
Michael Johnson - San Diego CA, US
Theodore Johnson - San Diego CA, US
Hiep Luu - San Diego CA, US
Cynthia Palmer - San Diego CA, US
Siegfried Reich - Solana Beach CA, US
Min Teng - San Diego CA, US
Christine Thomas - West Borough MA, US
Michael Varney - Solana Beach CA, US
Michael Wallace - San Diego CA, US
Michael Collins - San Diego CA, US
International Classification:
C07D471/02, A61K031/4745, A61K031/4162
US Classification:
514/303000, 514/406000, 546/119000, 548/361100
Abstract:
Indazole compounds that modulate and/or inhibit the activity of certain protein kinases are described. These compounds and pharmaceutical compositions containing them are capable of mediating tyrosine kinase signal transduction and thereby modulate and/or inhibit unwanted cell proliferation. The invention is also directed to the therapeutic or prophylactic use of pharmaceutical compositions containing such compounds, and to methods of treating cancer and other disease states associated with unwanted angiogenesis and/or cellular proliferation, such as diabetic retinopathy, neovascular glaucoma, rheumatoid arthritis, and psoriasis, by administering effective amounts of such compounds.
Indazole Compounds And Pharmaceutical Compositions For Inhibiting Protein Kinases, And Methods For Their Use
US Patent:
2004022, Nov 4, 2004
Filed:
Feb 15, 2003
Appl. No.:
10/326037
Inventors:
Robert Kania - San Diego CA, US
Steven Bender - Oceanside CA, US
Allen Borchardt - San Diego CA, US
Stephan Cripps - San Diego CA, US
Ye Hua - La Jolla CA, US
Michael Johnson - San Diego CA, US
Theodore Johnson - San Diego CA, US
Hiep Luu - San Diego CA, US
Cynthia Palmer - San Diego CA, US
Siegfried Reich - Solana Beach CA, US
Min Teng - San Diego CA, US
Christine Thomas - West Borough MA, US
Michael Varney - Solana Beach CA, US
Michael Wallace - San Diego CA, US
Michael Collins - San Diego CA, US
Steven Bender - Oceanside CA, US
Allen Borchardt - San Diego CA, US
Stephan Cripps - San Diego CA, US
Ye Hua - La Jolla CA, US
Michael Johnson - San Diego CA, US
Theodore Johnson - San Diego CA, US
Hiep Luu - San Diego CA, US
Cynthia Palmer - San Diego CA, US
Siegfried Reich - Solana Beach CA, US
Min Teng - San Diego CA, US
Christine Thomas - West Borough MA, US
Michael Varney - Solana Beach CA, US
Michael Wallace - San Diego CA, US
Michael Collins - San Diego CA, US
International Classification:
A61K031/416, C07D231/56
US Classification:
514/406000, 548/361100
Abstract:
Indazole compounds that modulate and/or inhibit the activity of certain protein kinases are described. These compounds and pharmaceutical compositions containing them are capable of mediating tyrosine kinase signal transduction and thereby modulate and/or inhibit unwanted cell proliferation. The invention is also directed to the therapeutic or prophylactic use of pharmaceutical compositions containing such compounds, and to methods of treating cancer and other disease states associated with unwanted angiogenesis and/or cellular proliferation, such as diabetic retinopathy, neovascular glaucoma, rheumatoid arthritis, and psoriasis, by administering effective amounts of such compounds.
Carbamate Compositions And Methods Fo Rmodulating The Activity Of The Chk1 Enzyme
US Patent:
2005014, Jul 7, 2005
Filed:
Aug 19, 2004
Appl. No.:
10/922337
Inventors:
Eugene Rui - San Diego CA, US
Theodore Johnson - San Diego CA, US
Jack Kellum - San Diego CA, US
Theodore Johnson - San Diego CA, US
Jack Kellum - San Diego CA, US
International Classification:
A61K031/43, A61K031/4184, A61K031/4188, C07D498/02, C07D277/84, C07D277/60
US Classification:
514366000, 514393000, 514394000, 548150000, 548302100, 548304100
Abstract:
Described herein are carbamate compounds. Such compounds are capable of modulating the activity of a checkpoint kinase, and described herein are methods for utilizing such modulation to treat cell proliferative disorders. Also described are pharmaceutical compositions containing such compounds. Also described are the therapeutic or prophylactic use of such compounds and compositions, and methods of treating cancer as well as other diseases associated with unwanted cellular proliferation, by administering effective amounts of such compounds in combination with anti-neoplastic agents.
Antipicornaviral Compounds And Compositons, Their Pharmaceutical Uses, And Materials For Their Synthesis
US Patent:
2003013, Jul 10, 2003
Filed:
Nov 6, 2002
Appl. No.:
10/289982
Inventors:
Peter Dragovich - Encinitas CA, US
Stephen Webber - San Diego CA, US
Thomas Prins - Cardiff CA, US
Ru Zhou - Carlsbad CA, US
Joseph Marakovits - Encinitas CA, US
Theodore Johnson - San Diego CA, US
Stephen Webber - San Diego CA, US
Thomas Prins - Cardiff CA, US
Ru Zhou - Carlsbad CA, US
Joseph Marakovits - Encinitas CA, US
Theodore Johnson - San Diego CA, US
International Classification:
A61K038/05, C07K005/04
US Classification:
514/019000, 548/316400, 560/169000
Abstract:
Peptido and peptidomimetic compounds of the formula:
wherein the formula variables are as defined in the disclosure, advantageously inhibit or block the biological activity of the picornaviral 3C protease. These compounds, as well as pharmaceutical compositions containing these compounds, are useful for treating patients or hosts infected with one or more picornaviruses, such as RVP. Intermediates and synthetic methods for preparing such compounds are also provided.
Antipicornaviral Compounds And Compositions, Their Pharmaceutical Uses, And Materials For Their Synthesis
US Patent:
2006004, Mar 2, 2006
Filed:
Aug 24, 2005
Appl. No.:
11/210717
Inventors:
Peter Dragovich - Encinitas CA, US
Stephen Webber - San Diego CA, US
Thomas Prins - Cardiff CA, US
Ru Zhou - Carlsbad CA, US
Joseph Marakovits - Encinitas CA, US
Theodore Johnson - San Diego CA, US
Stephen Webber - San Diego CA, US
Thomas Prins - Cardiff CA, US
Ru Zhou - Carlsbad CA, US
Joseph Marakovits - Encinitas CA, US
Theodore Johnson - San Diego CA, US
International Classification:
A61K 38/04, C07K 5/04, A61K 31/433, A61K 31/4245
US Classification:
514019000, 514362000, 514364000, 548128000, 548132000
Abstract:
Peptido and peptidomimetic compounds of the formula:
wherein the formula variables are as defined in the disclosure, advantageously inhibit or block the biological activity of the picornaviral 3C protease. These compounds, as well as pharmaceutical compositions containing these compounds, are useful for treating patients or hosts infected with one or more picornaviruses, such as RVP. Intermediates and synthetic methods for preparing such compounds are also provided.
Antipicornaviral Compounds And Compositions, Their Uses, And Materials For Their Synthesis
US Patent:
2003022, Dec 4, 2003
Filed:
May 12, 2003
Appl. No.:
10/435082
Inventors:
Theodore Johnson - San Diego CA, US
Ye Hua - La Jolla CA, US
Hiep Luu - San Diego CA, US
Peter Dragovich - Encinitas CA, US
Ye Hua - La Jolla CA, US
Hiep Luu - San Diego CA, US
Peter Dragovich - Encinitas CA, US
International Classification:
A61K031/675, A61K031/4196, A61K031/4162
US Classification:
514/114000, 514/383000, 514/400000, 548/112000, 548/263200, 548/316400
Abstract:
Compounds of the formula:
where the formula variables are as defined in the disclosure, advantageously inhibit or block the biological activity of the picornaviral 3C protease. These compounds, as well as pharmaceutical compositions containing these compounds, are useful for treating patients or hosts infected with one or more picornaviruses, such as RVP. Intermediates and synthetic methods for preparing such compounds are also described.
Antipicornaviral Compounds And Compositions, Their Pharmaceutical Uses, And Materials For Their Synthesis
US Patent:
2005008, Apr 14, 2005
Filed:
Jul 23, 2003
Appl. No.:
10/626827
Inventors:
Ye Hua - La Jolla CA, US
Hiep Luu - San Diego CA, US
Fora Chan - San Diego CA, US
Theodore Johnson - San Diego CA, US
Siegfried Reich - San Diego CA, US
Donald Skalitsky - San Diego CA, US
Yi Yang - San Diego CA, US
Thomas Hendrickson - Encinitas CA, US
Shao Chu - Encinitas CA, US
Brian Eastman - San Diego CA, US
Hiep Luu - San Diego CA, US
Fora Chan - San Diego CA, US
Theodore Johnson - San Diego CA, US
Siegfried Reich - San Diego CA, US
Donald Skalitsky - San Diego CA, US
Yi Yang - San Diego CA, US
Thomas Hendrickson - Encinitas CA, US
Shao Chu - Encinitas CA, US
Brian Eastman - San Diego CA, US
International Classification:
A61K031/4196, A61K031/4178, A61K031/4025, C07D043/02
US Classification:
514383000, 514397000, 514422000, 548263200, 548311100, 548517000
Abstract:
Compounds of the formula:
where the formula variables are as defined in the disclosure, advantageously inhibit or block the biological activity of the picomaviral 3C protease. These compounds, as well as pharmaceutical compositions containing these compounds, are useful for treating patients or hosts infected with one or more picornaviruses, such as RVP. Intermediates and synthetic methods for preparing such compounds are also described.
Antipicornaviral Compounds And Compositions, Their Pharmaceutical Uses, And Materials For Their Synthesis
US Patent:
2005010, May 12, 2005
Filed:
Nov 12, 2004
Appl. No.:
10/986109
Inventors:
Theodore Johnson - San Diego CA, US
Ye Hua - La Jolla CA, US
Hiep Luu - San Diego CA, US
Peter Dragovich - Encinitas CA, US
Ye Hua - La Jolla CA, US
Hiep Luu - San Diego CA, US
Peter Dragovich - Encinitas CA, US
International Classification:
A61K031/4178, A61K031/4164, C07D043/02, A61K031/41
US Classification:
514381000, 514386000, 548251000, 548324100, 548311100
Abstract:
Compounds of the formula:
where the formula variables are as defined in the disclosure, advantageously inhibit or block the biological activity of the picomaviral 3C protease. These compounds, as well as pharmaceutical compositions containing these compounds, are useful for treating patients or hosts infected with one or more picomaviruses, such as RVP. Intermediates and synthetic methods for preparing such compounds are also described.