DR. THEODORE MALININ
Medical Practice at 10 Ave, Miami, FL

2007013, Jun 14, 2007

Feb 21, 2007

11/677414

Theodore Malinin - Key Biscayne FL, US

A61F 2/28

623016110, 606086000

Provided are procedures and instruments for preparing and transplanting osteochondral allograft plugs to a host bone to repair an articular cartilage defect. An allograft bone plug having a cartilage plate and cancellous bone tissue attached thereto is removed from a donor bone. The allograft plug is further shaped by removing or cutting away cancellous bone tissue to form a cancellous stalk extending from the cartilage plate. The formed cancellous stalk can have any suitable shape including cylindrical, conical, and rectilinear. At the recipient site of the host bone, a cutout is formed corresponding in shape to the allograft plug. The allograft plug is inserted into the cutout such that the cancellous stalk is retained in the host bone and the cartilage plate aligns with the condyle surface of the host bone. Aspects of the invention may also be applicable to preparing and transplanting osteochondral autograft plugs.

7371260, May 13, 2008

Oct 26, 2005

11/259749

Theodore I. Malinin - Key Biscayne FL, US

Biomet Sports Medicine, Inc. - Warsaw IN

A61F 2/38, A61F 5/00, A61B 17/00

623 1412, 606 80, 606 86, 606 87, 606 96, 600567

Provided are procedures and instruments for preparing and transplanting osteochondral allograft plugs to a host bone to repair an articular cartilage defect. An allograft bone plug having a cartilage plate and cancellous bone tissue attached thereto is removed from a donor bone. The allograft plug is further shaped by removing or cutting away cancellous bone tissue to form a cancellous stalk extending from the cartilage plate. The formed cancellous stalk can have any suitable shape including cylindrical, conical, and rectilinear. At the recipient site of the host bone, a cutout is formed corresponding in shape to the allograft plug. The allograft plug is inserted into the cutout such that the cancellous stalk is retained in the host bone and the cartilage plate aligns with the condyle surface of the host bone. Aspects of the invention may also be applicable to preparing and transplanting osteochondral autograft plugs.

2012028, Nov 8, 2012

Jan 10, 2011

13/520734

H. Thomas Temple - Miami FL, US
Theodore I. Malinin - Key Biscayne FL, US
Siu Tung Wu - Miami FL, US

A61F 2/08

623 1311

Cruciate ligament substitutes are formed using fan-folded fascia lata grafts. Devices of making the same and methods of making and using the same are described herein. The fan-folded fascia lata cruciate ligament substitutes disclosed herein are used in a single-loop fashion and have surprisingly exhibited load to failure and stiffness values that compare favorably with conventional grafts, including tibialis anterior, tibialis posterior, peroneus longus, and bone-patellar tendon-bone (BPTB) half-patella specimens. It has been demonstrated that single-loop, fan-folded fascia lata sheets can exhibit mechanical properties that compare favorably with existing cruciate ligament grafts. An apparatus for handling a fascia lata sheet can include a first and a second removable anchoring member. A method of producing a cruciate ligament substitute can include providing a fascia lata sheet secured in a fan-folded orientation with at least one removable anchoring member, and securing the fan-folded fascia lata in a fan-folded orientation with at least one permanent anchoring member.

2011020, Aug 25, 2011

Aug 5, 2009

13/057918

Theodore Malinin - Key Biscayne FL, US
Temple H. Thomas - Miami FL, US

UNIVERSITY OF MIAMI - MIAMI FL

A61F 2/08, A61F 2/28

623 1314, 623 1611

A solid implantable bone construct () shaped like a cylinder, a cone, or a frustum, for anchoring ligament implants. The bone construct () can include a bone component and a biocompatible solid component. The bone component can include particulate bone of between 75 and 600 microns, powdered bone of 75 microns or smaller in size, or both. The biocompatible solid component can include calcium sulfate hemihydrate, a calcium phosphate product, or both. The bone component can be between 5 and 50 wt-% of the construct () and the biocompatible solid component can be at least 50 wt-% of the construct (). Also disclosed is a composite graft () comprising a first bone dowel () and a ligament () and a method of securing one bone to another using the composite graft ().

7550007, Jun 23, 2009

Feb 23, 2007

11/678453

Theodore I. Malinin - Key Biscayne FL, US

Biomet Sports Medicine, LLC - Warsaw IN

A61F 2/08, A61F 2/28

623 1412, 623 2363

Provided are procedures and instruments for preparing and transplanting osteochondral allograft plugs to a host bone to repair an articular cartilage defect. An allograft bone plug having a cartilage plate and cancellous bone tissue attached thereto is removed from a donor bone. The allograft plug is further shaped by removing or cutting away cancellous bone tissue to form a cancellous stalk extending from the cartilage plate. The formed cancellous stalk can have any suitable shape including cylindrical, conical, and rectilinear. At the recipient site of the host bone, a cutout is formed corresponding in shape to the allograft plug. The allograft plug is inserted into the cutout such that the cancellous stalk is retained in the host bone and the cartilage plate aligns with the condyle surface of the host bone. Aspects of the invention may also be applicable to preparing and transplanting osteochondral autograft plugs.

7838040, Nov 23, 2010

Nov 28, 2006

11/564012

Theodore Malinin - Key Biscayne FL, US

A61K 35/34

424548, 424549

Disclosed is a method for regenerating articular cartilage in an animal comprising administering a therapeutically effective amount of a non-demineralized particulate articular cartilage having a distribution of particle sizes within the range of from about 60 microns to about 500 microns.

2008027, Nov 13, 2008

May 10, 2007

11/746877

Theodore I. Malinin - Key Biscayne FL, US

A61K 35/32, A61F 2/02

424 937, 424548, 623 1111

Cartilage materials such as cartilage fluff and a cartilage composition comprising a particulate material are disclosed. These are suitable for stimulating chondrogenesis and/or producing cartilage regeneration. Also disclosed are processes for their preparation. Methods for regenerating articular cartilage are also disclosed, which involve, for example, placing the cartilage fluff or cartilage composition into a cartilage defect.

2013033, Dec 12, 2013

Aug 14, 2013

13/966676

Theodore I. Malinin - Key Biscayne FL, US

VIVEX BIOMEDICAL INC. - Marietta GA

A61L 27/36

424423, 424548, 424 937, 424 9371

Cartilage materials such as cartilage fluff and a cartilage composition comprising a particulate material are disclosed. These are suitable for stimulating chondrogenesis and/or producing cartilage regeneration. Also disclosed are processes for their preparation. Methods for regenerating articular cartilage are also disclosed, which involve, for example, placing the cartilage fluff or cartilage composition into a cartilage defect.