Theodore H Stanley
Physician in Salt Lake City, UT

6488959, Dec 3, 2002

May 24, 2001

09/864472

Theodore Stanley - Salt Lake City UT
Wade Hull - Taylorsville UT
Larry Rigby - Salt Lake City UT
Jie Zhang - Salt Lake City UT

Zars, Inc. - Salt Lake City UT

A61F 1300

424449, 424448, 424447, 604 20

The present invention relates to a transdermal drug delivery system comprising a dermal drug delivery patch and a heating element compartment securable to the dermal drug delivery patch. A freely transferrable heating element is securable within the heating element compartment. A drug can be administered transdermally using the present invention by placing the dermal drug delivery patch upon a patients skin at an administration site. A heating element compartment is secured to the dermal drug delivery patch and a freely transferrable heating element is placed within the heating element compartment. The heating element provides controlled heat to the dermal drug patch and the patients skin and thereby improves dermal drug administration.

4863737, Sep 5, 1989

Jun 8, 1987

7/060045

Theodore H. Stanley - Salt Lake City UT
Brian Hague - West Valley UT

University of Utah - Salt Lake City UT

A61K 968

424440

Compositions and methods of manufacture for producing a medicament composition capable of absorption through the mucosal tissues of the mouth, pharynx, and esophagus. The present invention relates to such compositions and methods which are useful in administering drugs in a dose-to-effect manner such that sufficient drug is administered to produce precisely a desired effect. The invention also relates to a manufacturing technique that enables a therapeutic agent or drug to be incorporated into a flavored confectionary base and to compress or otherwise attach the solid confectionary mixture onto an appliance or holder. Employing the present invention, the drug may be introduced into the patient's bloodstream almost as fast as through injection, and much faster than using the oral administration route, while avoiding the negative aspects of both of these methods. The present invention achieves these advantages by incorporating the drug into a compressed powder "candy " matrix. The pH and pKa of the powder matrix can be modified to increase the absorption of the drug through the mucosal tissues.

5288497, Feb 22, 1994

Sep 5, 1989

7/403751

Theodore H. Stanley - Salt Lake City UT
Brian Hague - West Valley City UT

The University of Utah - Salt Lake City UT

A61K 968

424440

Compositions and methods of manufacture for producing a medicament composition capable of absorption through the mucosal tissues of the mouth, pharynx, and esophagus. The present invention relates to such compositions and methods which are useful in administering lipophilic and nonlipophilic drugs in a dose-to-effect manner that sufficient drug is administered to produce precisely a desired effect. The invention also relates to a manufacturing technique that enables a therapeutic agent or drug to be incorporated into a flavored dissolvable matrix. An appliance or holder is preferably attached to the dissolvable matrix. Employing the present invention the drug may be introduced into the patient's bloodstream almost as fast as through injection, and much faster than using the oral administration route, while avoiding the negative aspects of both of these methods. The present invention achieves these advantages by incorporating the drug into a carbohydrate, fat, protein, wax, or other dissolvable matrix composition. The dissolvable matrix may include permeation enhancers to increase the drug absorption by the mucosal tissues of the mouth.

6955819, Oct 18, 2005

Feb 28, 2001

09/796250

Jie Zhang - Salt Lake City UT, US
Wade Hull - Taylorsville UT, US
Larry Rigby - Salt Lake City UT, US
Theodore Stanley - Salt Lake City UT, US

Zars, Inc. - Salt Lake City UT

A61K009/70, A61F013/00

424449, 424401, 424443, 424447

The present invention is directed toward an apparatus to rapidly deliver a drug to a patient The invention comprises a drug beneath a patient's skin in a drug depot site. A heating component is placed near the drug depot site and generates heat in and near the drug depot site. A control component connected to the heating component is used to control the magnitude and duration of heat generated by the heating component.

5783207, Jul 21, 1998

Feb 4, 1997

8/795359

Theodore H. Stanley - Salt Lake City UT
Brian Hague - West Valley City UT

University of Utah Research Foundation - Salt Lake City UT

A61K 968, A61K 31465

424440

The present invention relates to a selectively removable nicotine-containing dosage form for use in the transmucosal delivery of nicotine to a patient. More specifically, the present invention is directed to a nicotine-containing dosage-form comprising an attached holder member which may be used to manipulate the dosage form within the mouth of the patient as part of an effective smoking cessation program or in situations where smoking is undesirable or not permitted. Nicotine is released from a dosage form and absorbed through the intra-oral mucosal surfaces as the nicotine-containing matrix releases nicotine within the user's mouth. The user may selectively insert and remove the dosage form as desired to control the release of nicotine. In addition, the user may manipulate the dosage form by use of the holder means in such a manner to meet the user's psychological need or desire for ritualistic oral stimulation similar to cigarette smoking.

5291887, Mar 8, 1994

Jun 2, 1992

7/892287

Theodore H. Stanley - Salt Lake City UT
Jie Zhang - West Valley UT

Anesta Corporation - Salt Lake City UT

A61B 500

128637

The present invention is directed to novel methods and apparatus for noninvasively collecting substances through mucosal tissues. The concentration of a substance in blood is monitored noninvasively by correlation with the amount of the substance which permeates a mucosal membrane into a substance receiving medium over a specified time period. The substance receiving medium may include an substance permeation enhancer capable of increasing the substance permeability across the mucosal membrane. The substance receiving medium is positioned against the mucosal membrane. After sufficient time delay, the substance receiving medium is removed and analyzed for the concentration of a substance to be measured using known analytical techniques. The apparatus within the scope of the present invention includes means for supporting the substance receiving medium. The means for supporting the receiving medium provides an added benefit of isolating the substance receiving medium from contamination sources.

5132114, Jul 21, 1992

Sep 5, 1989

7/402881

Theodore H. Stanley - Salt Lake City UT
Brian Hague - West Valley City UT

University of Utah Research Foundation - Salt Lake City UT

A61K 968

424440

Compositions and methods of manufacture for producing a medicament composition capable of absorption through the mucosal tissues of the mouth, pharynx, and esophagus. The present invention relates to such compositions and methods which are useful in administering drugs in a dose-to-effect manner such that sufficient drug is administered to produce precisely a desired effect. The invention also relates to a manufacturing technique that enables a therapeutic agent or drug to be incorporated into a flavored confectionary base and to compress or otherwise attach the solid confectionary mixture onto an appliance or holder. Employing the present invention the drug may be introduced into the patient's bloodstream almost as fast as through injection, and much faster than using the oral administration route, while avoiding the negative aspects of both of these methods. The present invention achieves these advantages by incorporating the drug into a compressed powder "candy" matrix. The pH and pKa of the powder matrix can be modified to increase the absorption of the drug through the mucosal tissues.

4885173, Dec 5, 1989

Jun 8, 1987

7/060046

Theodore H. Stanley - Salt Lake City UT
Brian Hague - West Valley City UT

University of Utah - Salt Lake City UT

A61K 968

424440

2007016, Jul 19, 2007

Mar 13, 2007

11/685394

Daniel Vezina - Park City UT, US
Theodore Stanley - Salt Lake City UT, US

University of Utah Research Foundation - Salt Lake City UT

G06F 17/30

707003000

Techniques for providing expert instruction in interpreting outputs of a test instrument to a student who is at a location remote from the expert. The student makes outputs from the test instrument and an interpretation of the outputs available to an expert via a network and receives a commented and graded response in return. The outputs, the interpretation, and the response may be made available in real time or in non-real time. In the non-real-time embodiment, the student makes his interpretation by selecting from menus of possible observations, the expert does the same, and the two interpretations are automatically compared to produce the comments and grade for the response. One application of the invention is teaching echocardiography.

3985141, Oct 12, 1976

Mar 10, 1975

5/557192

Theodore H. Stanley - Salt Lake City UT
Jerrold L. Foote - Salt Lake City UT

The University of Utah - Salt Lake City UT

A61M 1600

128351

An inflation and adjustable pressure relief apparatus for the inflatable cuff of an endotracheal tube, the apparatus having an adjustably spring-biased relief valve to automatically release gas pressures from the cuff above a preselected pressure level and a manually operable spring-biased valve for increasing the gas pressure in the cuff.