TAUSEEF AHMED
Pharmacy in Briarcliff, NY
License number
Michigan 4301040644
Expiration Date
Jun 30, 1980
Category
Pharmacy
Type
CS - 3
Address
Address
Briarcliff, NY 10510
Professional information
Taxane Analogs For The Treatment Of Brain Cancer
US Patent:
8409574, Apr 2, 2013
Filed:
Aug 20, 2010
Appl. No.:
12/859990
Inventors:
James D. McChesney - Etta MS, US
Gilles Tapolsky - Boulder CO, US
David E. Emerson - Longmont CO, US
John Marshall - Washington DC, US
Tauseef Ahmed - Briarcliff Manor NY, US
Allen Cohn - Englewood CO, US
Michael Kurman - Upper Saddle River NJ, US
Manuel Modiano - Tucson AZ, US
Gilles Tapolsky - Boulder CO, US
David E. Emerson - Longmont CO, US
John Marshall - Washington DC, US
Tauseef Ahmed - Briarcliff Manor NY, US
Allen Cohn - Englewood CO, US
Michael Kurman - Upper Saddle River NJ, US
Manuel Modiano - Tucson AZ, US
International Classification:
A61K 39/00, A61K 31/415, A61K 31/335, A01N 43/52, A01N 43/32, C07D 309/00
US Classification:
4241331, 514393, 514452, 549358
Abstract:
Provided herein are compounds and methods for the treatment of brain cancer in a mammal, wherein the method comprises the administration to the mammal a compound that stabilizes tubulin dimers or microtubles at G2-M interface during mitosis but is not a substrate for MDR protein. In particular, the present application relates to the use of an orally effective abeo-taxane, alone or in combination with temozolomide or bevacizumab, for the treatment of brain cancer.
Taxane Analogs For The Treatment Of Brain Cancer
US Patent:
2013025, Sep 26, 2013
Filed:
Mar 5, 2013
Appl. No.:
13/785753
Inventors:
Gilles Tapolsky - Louisville KY, US
David E. Emerson - Longmont CO, US
John Marshall - Washington DC, US
Tauseef Ahmed - Briarcliff Manor NY, US
Allen Cohn - Englewood CO, US
Michael Kurman - Upper Saddle River NJ, US
Manuel Modiano - Tucson AZ, US
David E. Emerson - Longmont CO, US
John Marshall - Washington DC, US
Tauseef Ahmed - Briarcliff Manor NY, US
Allen Cohn - Englewood CO, US
Michael Kurman - Upper Saddle River NJ, US
Manuel Modiano - Tucson AZ, US
International Classification:
A61K 31/357
US Classification:
514452, 549358
Abstract:
Provided herein are compounds and methods for the treatment of brain cancer in a mammal, wherein the method comprises the administration to the mammal a compound that stabilizes tubulin dimers or microtubles at G2-M interface during mitosis but is not a substrate for MDR protein. In particular, the present application relates to the use of an orally effective abeo-taxane, alone or in combination with temozolomide or bevacizumab, for the treatment of brain cancer.