TAHER MOHAMED HEGAB, B.PHARM PH.D
Pharmacy at Nees Ave, Fresno, CA

License number

California 60535

Professional information

Taher Hegab - Fresno, CA

Work:

Misr International University
Faculty of pharmacy Clovis Community Medical Center
Pharmacist Rite Aid Corporation - Fresno, CA
Pharmacist State University of NY at Buffalo - Buffalo, NY
Teaching Assistant Kinex pharmaceuticals - Buffalo, NY
Chemist Ali's Image pharmacies - Cairo, GA
Pharmacist/Pharmacy Manager Al-Azhar University - Cairo
Faculty of Pharmacy

Education:

University of Florida, College of Pharmacy - Gainesville, FL
PharmD State University of NY at Buffalo - Buffalo, NY
PhD in Medicinal Chemistry Azhar University - Cairo
Bachelor of Science in Pharmacy

Azepans And Methods For Making And Using Same

US Patent:

2008016, Jul 3, 2008

Filed:

Dec 6, 2007

Appl. No.:

11/999723

Inventors:

David G. Hangauer - East Amherst NY, US
Fengzhi Li - Buffalo NY, US
Taher Hegab - Fresno CA, US
Xiang Ling - Snyder NY, US

International Classification:

C07D 403/04

US Classification:

540524

Abstract:

Disclosed are compounds having the formula:wherein Zis an alkylene moiety; Q is a carboxylic acid derivative; and Rand Rare the same or different and are selected from the group consisting of alkyl, aryl, alkylcarbonyl, arylcarbonyl, hydroxycarbonyl, and alkoxycarbonyl or Rand R, taken together with the nitrogen atom to which they are bound, form a ring. Also disclosed are compounds having the formula:wherein Zis an alkylene moiety; Q is a carboxylic acid derivative; and Ris selected from the group consisting of alkyl and aryl. The compounds can be used to modulate cell proliferation and/or apoptosis, for example, in the treatment of cancers and other proliferative diseases, disorders, and conditions.