Inventors:
Todd Charlton Sacktor - Yonkers NY, US
John Fonda Crary - New York NY, US
Alejandro Ivan Hernandez - Queens NY, US
Suzanne Mirra - Brooklyn NY, US
Charles Shao - Forest Hills NY, US
Assignee:
Research Foundation of State of University of New York - Albany NY
International Classification:
C07K 16/00
Abstract:
The present invention establishes a link between altered aPKC function and nervous system disorders and cancers, such as Alzheimer's disease (AD) and neuroblastoma. Methods of using aPKC in diagnosis, drug screening and gene therapy in nervous system disorders and cancers are provided.