Inventors:
James Eshleman - Lutherville MD, US
Chanjuan Shi - Lutherville MD, US
Susan Eshleman - Lutherville MD, US
International Classification:
C12Q 1/70, C12Q 1/68
Abstract:
The invention provides methods permitting the detection of small amounts of different nucleic acids in the presence of an excess amount of wild-type nucleic acids. Also provided herein are method so detecting infectious disease minority variants, methods of forensic identification, methods of diagnosing cancer and monitoring disease progress.