SUBRAMANIAM SRIRAM, MD
Osteopathic Medicine in Nashville, TN

License number
Tennessee MD24854
Category
Medical Practice
Type
Neurological Surgery
License number
Tennessee MD24854
Category
Neurology
Type
Neurology
License number
Tennessee MD24854
Category
Osteopathic Medicine
Type
Internal Medicine
Address
Address
3601 Tvc, Nashville, TN 37232
Phone
(615) 322-3000

Organization information

See more information about SUBRAMANIAM SRIRAM at bizstanding.com

Subramaniam Sriram MD

719 Thompson Ln, Nashville, TN 37204

Industry:
Neurologist, Neurosurgeon, Internist
Phone:
(615) 322-4475 (Phone)
Subramaniam Sriram


Subramaniam Sriram MD

3810 Bedford Ave STE 100, Nashville, TN 37215

Categories:
Internal Medicine Physicians & Surgeons
Phone:
(615) 499-4545 (Phone)

Professional information

Subramaniam Sriram Photo 1

Methods And Treatment Of Multiple Sclerosis

US Patent:
6710033, Mar 23, 2004
Filed:
Mar 17, 2000
Appl. No.:
09/528348
Inventors:
Charles W. Stratton - Nashville TN
William M. Mitchell - Nashville TN
Subramaniam Sriram - Nashville TN
Assignee:
Vanderbilt University - Nashville TN
International Classification:
A61K 3170
US Classification:
514 29, 514 31, 514311, 514312, 514313, 514314, 514398, 514903
Abstract:
The invention features methods and reagents for the diagnosis, monitoring, and treatment of multiple sclerosis. The invention is based in part on the discovery that Chlamydia is present in patients with multiple sclerosis, and that anti-chlamydial agents improve or sustain neurological function in these patients.


Subramaniam Sriram Photo 2

Protein Kinase Inhibitor

US Patent:
6555702, Apr 29, 2003
Filed:
Apr 3, 1998
Appl. No.:
09/054971
Inventors:
Subramaniam Sriram - Nashville TN
John Bright - Nashville TN
Bishwajit Nag - Fremont CA
Somesh D. Sharma - Los Altos CA
Assignee:
Calyx Therapeutics, Inc. - Hayward CA
International Classification:
A61K 3121
US Classification:
558401, 558391, 558392, 514514, 514523, 514525
Abstract:
A compound of the formula I: wherein A and C are independently H, alkyl of 1-6 carbon atoms, hydroxy, or alkoxy of 1-6 carbon atoms; B is hydroxy, alkoxy of 1-6 carbon atoms —CO Z, —O(CH ) CO Z, —SO Z, —OPO Z ; and Y is cyano,   —C(NR R ) C(CN) ; wherein X O or S, and R and R are independently H, benzyl, —CH(CH )C H , —(CH ) C H , phenyl; —CO R; n=2-4; R is lower alkyl of 1-6 carbon atoms; m=1-4 and Z is H, a cation or lower alkyl of 1-6 cabon atoms; is used for treating inflammation, immunological diseases or diabetes.


Subramaniam Sriram Photo 3

Protein Kinase Inhibitor

US Patent:
6194453, Feb 27, 2001
Filed:
Dec 21, 1998
Appl. No.:
9/218264
Inventors:
Subramaniam Sriram - Nashville TN
John Bright - Nashville TN
Bishwajit Nag - Fremont CA
Somesh D. Sharma - Los Altos CA
Assignee:
Calyx Therapeutics, Inc. - Hayward CA
International Classification:
A61K 3121, A61K 3126, A61K 31275
US Classification:
514514
Abstract:
Disclosed herein are compounds of the formula I ##STR1## wherein A and C are independently H, alkyl of 1-6 carbon atoms, hydroxy, or alkoxy of 1-6 carbon atoms; B is hydroxy or alkoxy of 1-6 carbon atoms; and Y is cyano, ##STR2## --C(NR. sub. 1 R. sub. 2). dbd. C(CN). sub. 2 ; wherein X. dbd. O or S, and R. sub. 1 and R. sub. 2 are independently H, benzyl, --CH(CH. sub. 3)C. sub. 6 H. sub. 6, --(CH. sub. 2). sub. n C. sub. 6 H. sub. 6, phenyl; --CO. sub. 2 R; n=2-4; R is lower alkyl of 1-6 carbon atoms which are useful for treating inflammation and immunological diseases.


Subramaniam Sriram Photo 4

Vaccination With Peptide Of Mhc Class Ll Molecules For Treatment Of Autoimmune Disease

US Patent:
2004018, Sep 16, 2004
Filed:
Feb 15, 2002
Appl. No.:
10/078075
Inventors:
Subramaniam Sriram - Nashville TN, US
Bishwajit Nag - Fremont CA, US
Somesh Sharma - Los Altos CA, US
International Classification:
A61K039/00
US Classification:
424/185100, 514/014000
Abstract:
The present invention provides immunogenic oligopeptides derived from the Major Histocompatibility Complex (MHC) glycoprotein protein sequences for use in compositions and methods for the treatment, prevention and diagnosis of deleterious immune responses, such as autoimmunity and allergies. The peptides are capable of inducing an immune response against glycoproteins encoded MHC alleles associated with the target disease. In preferred embodiments the peptides of the invention are derived from hypervariable region of the chain of an MHC Class II molecule associated with the deleterious immune response.


Subramaniam Sriram Photo 5

Vaccination With Peptide Of Mhc Class Ii Molecules For Treatment Of Autoimmune Disease

US Patent:
6045796, Apr 4, 2000
Filed:
Jun 7, 1995
Appl. No.:
8/485617
Inventors:
Subramaniam Sriram - Nashville TN
Bishwajit Nag - Fremont CA
Somesh D. Sharma - Los Altos CA
Assignee:
Anergen, Inc. - Redwood City CA
International Classification:
A61K 3900, C07K 1474
US Classification:
4241851
Abstract:
The present invention provides immunogenic oligopeptides derived from the Major Histocompatibility Complex (MHC) glycoprotein protein sequences for use in compositions and methods for the treatment, prevention and diagnosis of deleterious immune responses, such as autoimmunity and allergies. The peptides are capable of inducing an immune response against glycoproteins encoded MHC alleles associated with the target disease. In preferred embodiments the peptides of the invention are derived from hypervariable region of the. beta. chain of an MHC Class II molecule associated with the deleterious immune response.


Subramaniam Sriram Photo 6

Protein Kinase Inhibitor

US Patent:
5854285, Dec 29, 1998
Filed:
Apr 3, 1997
Appl. No.:
8/825662
Inventors:
Subramaniam Sriram - Nashville TN
John Bright - Nashville TN
Bishwajit Nag - Fremont CA
Somesh D. Sharma - Los Altos CA
Assignee:
Natpro, Inc. - Union City CA
International Classification:
A61K 3121, A61K 3126, A61K 31275
US Classification:
514514
Abstract:
A compound of the formula I ##STR1## wherein A and C are independently H, alkyl of 1-6 carbon atoms, hydroxy, or alkoxy of 1-6 carbon atoms; B is hydroxy or alkoxy of 1-6 carbon atoms; and Y is cyano, ##STR2## --C(NR. sub. 1 R. sub. 2). dbd. C(CN). sub. 2 ; wherein X=O or S, and R. sub. 1 and R. sub. 2 are independently H, benzyl, --CH(CH. sub. 3), C. sub. 6 H. sub. 5 --(CH. sub. 2). sub. n C. sub. 6 H. sub. 6, phenyl; --CO. sub. 2 R; n=2-4; R is lower alkyl of 1-6 carbon atoms is used for treating inflammation and immunological diseases.


Subramaniam Sriram Photo 7

Methods And Reagents For The Treatment Of Multiple Sclerosis

US Patent:
6890526, May 10, 2005
Filed:
Apr 17, 2003
Appl. No.:
10/419034
Inventors:
Charles W. Stratton - Nashville TN, US
William M. Mitchell - Nashville TN, US
Subramaniam Sriram - Nashville TN, US
Assignee:
Vanderbilt University - Nashville TN
International Classification:
A61K038/21, A61K031/7048, A61K031/496, A61K031/65, A61K031/18
US Classification:
424 854, 514 28, 514152, 514192, 51425213, 51425308
Abstract:
The invention features methods and reagents for the diagnosis, monitoring, and treatment of multiple sclerosis. The invention is based in part on the discovery that is present in patients with multiple sclerosis, and that anti-chlamydial agents improve or sustain neurological function in these patients.


Subramaniam Sriram Photo 8

Methods And Reagents For The Treatment Of Multiple Sclerosis

US Patent:
7094397, Aug 22, 2006
Filed:
Feb 17, 2005
Appl. No.:
11/060088
Inventors:
Charles W. Stratton - Nashville TN, US
William M. Mitchell - Nashville TN, US
Subramaniam Sriram - Nashville TN, US
Assignee:
Vanderbilt Unversity - Nashville TN
International Classification:
A61K 38/21, A61K 31/7048, A61K 31/496, A61K 31/65, A61K 31/18
US Classification:
424 854, 514152, 514192, 51425213, 51425301, 514 28, 514291, 514312, 514602
Abstract:
The invention features methods and reagents for the diagnosis, monitoring, and treatment of multiple sclerosis. The invention is based in part on the discovery that is present in patients with multiple sclerosis, and that anti-chlamydial agents improve or sustain neurological function in these patients.