Inventors:
Subramaniam Sriram - Nashville TN
John Bright - Nashville TN
Bishwajit Nag - Fremont CA
Somesh D. Sharma - Los Altos CA
Assignee:
Calyx Therapeutics, Inc. - Hayward CA
International Classification:
A61K 3121
US Classification:
558401, 558391, 558392, 514514, 514523, 514525
Abstract:
A compound of the formula I: wherein A and C are independently H, alkyl of 1-6 carbon atoms, hydroxy, or alkoxy of 1-6 carbon atoms; B is hydroxy, alkoxy of 1-6 carbon atoms âCO Z, âO(CH ) CO Z, âSO Z, âOPO Z ; and Y is cyano, â âC(NR R ) C(CN) ; wherein X O or S, and R and R are independently H, benzyl, âCH(CH )C H , â(CH ) C H , phenyl; âCO R; n=2-4; R is lower alkyl of 1-6 carbon atoms; m=1-4 and Z is H, a cation or lower alkyl of 1-6 cabon atoms; is used for treating inflammation, immunological diseases or diabetes.