Inventors:
Stewart A. Anderson - New York NY, US
Asif Maroof - New York NY, US
Lorenz Studer - New York NY, US
Assignee:
SLOAN KETTERING INSTITUTE FOR CANCER RESEARCH - New York NY
CORNELL UNIVERSITY - Ithaca NY
International Classification:
A61K 35/12, C12N 5/10, A61P 25/18, A61P 25/08, A61P 25/00, A61P 25/22, C12P 21/06, A61P 25/16
US Classification:
424 9321, 435 691, 435325, 435366
Abstract:
The present invention relates to methods of isolating a purified or enriched population of cortical or striatal immature interneuron progenitor cells and the isolated purified or enriched population of immature interneuron progenitor cells. Methods of treating a condition mediated by a loss or deficiency of interneuron function using the purified or enriched population of immature interneuron progenitor cells are also disclosed.