STEWART A ANDERSON
Medical Practice in San Francisco, CA
License number
Pennsylvania MD048386L
Category
Medicine
Type
Medical Physician and Surgeon
Address
Address
2
San Francisco, CA 94122
Pennsylvania
Pennsylvania
Personal information
See more information about STEWART A ANDERSON at radaris.comName
Address
Phone
604 Via Promontorio, San Clemente, CA 92672
6359 Burchfield Ave, Pittsburgh, PA 15217
640 Pine St, Philadelphia, PA 19106
9548 Svl Box, Victorville, CA 92395
771 Eagle Ave, Alameda, CA 94501
Professional information
Production Of Gabaergic Cells
US Patent:
6602680, Aug 5, 2003
Filed:
Jul 5, 2001
Appl. No.:
09/900527
Inventors:
John L. Rubenstein - San Francisco CA
Marina Mione - London, GB
Stewart Anderson - San Francisco CA
Thorsten Stuehmer - San Francisco CA
Kyuson Yun - San Francisco CA
Marina Mione - London, GB
Stewart Anderson - San Francisco CA
Thorsten Stuehmer - San Francisco CA
Kyuson Yun - San Francisco CA
Assignee:
The Regents of the University of California - Oakland CA
International Classification:
C12Q 168
US Classification:
435 29, 435 6, 4353201, 435455, 536 231, 536 232, 536 235, 424 937
Abstract:
The invention features methods and compositions for the production of GABAergic cells, particularly GABAergic neurons. Production of GABAergic cells is accomplished by increasing activity of a Dlx gene (e. g. , DLX1, DLX2, or DLX5) in an immature neuronal cell. The increase in Dlx activity causes differentiation of the immature neuronal cell into a neuronal cell exhibiting the GABAergic phenotype. The invention also encompasses use of GABAergic cells produced by the method of the invention in, for example, identification of agents that affect GABAergic cell activity and survival, and in replacement therapy.