Inventors:
Steven T. DeKosky - Pittsburgh PA
M. Ilyas Kamboh - Pittsburgh PA
Assignee:
University of Pittsburgh - Pittsburgh PA
International Classification:
C07H 2104, C12Q 168, C12P 1934, G01N 3353
Abstract:
The invention is directed to a method for screening for the risk of developing Alzheimer's disease (AD) in a subject by detecting the presence or absence of the APOE4 allele and the presence or absence of the ACT alleles which modify the risk of AD associated with the APOE4 allele. The invention offers a non-invasive method to identify individuals at high risk for the development of AD.