Inventors:
Douglas W. Danielson - Otsego MI, US
Steven S. Schuehle - Allegan MI, US
Shirish A. Shah - Kalamazoo MI, US
Assignee:
L. Perrigo Company - Allegan MI
International Classification:
A61K 9/14, A61K 9/20, A61K 9/48
US Classification:
424464, 424451, 424452, 424465, 424489
Abstract:
A process and pharmaceutical composition containing simethicone and magnesium carbonate allows a higher production rate of simethicone containing tablets and a more consistent end product tablet. The magnesium carbonate prevents sticking of simethicone to tablet compressing apparatuses, and may also prevent sticking of other excipients to tablet compressing apparatuses.