Minnesota Headache Center - Steven S Lebow MD<br>Minnesota Headache Center - Beth A Staab MD<br>Minnesota Headache Center - Vanda R Fickel Niemi MD<br>Minnesota Headache Center - Lawrence Burstein MD<br>Minnesota Headache Center<br>Minnesota Headache Center - Mary Jane Chiasson Do
Methods And Systems For Regional Synchronous Neural Interactions Analysis
US Patent:
2011019, Aug 4, 2011
Filed:
Feb 1, 2011
Appl. No.:
13/019135
Inventors:
Todd A. Verdoorn - Minneapolis MN, US Michael Cassano - Minneapolis MN, US Rajasimhan Rajagovindan - St. Louis Park MN, US Steven Lebow - Minneapolis MN, US
International Classification:
A61B 5/055
US Classification:
600411
Abstract:
Systems and methods for quantifying neurophysiologic activity of a subject. A set of subject data representing a time series of neurophysiologic activity acquired by each of a multiplicity of spatially distributed sensors arranged to detect neural signaling in the subject is received. A time series of data obtained from each of the sensors is associated with a corresponding neural population within the brain of the subject. Interaction sets among at least two neural populations in the brain of the subject are determined based on a statistical analysis of a plurality of time series of data from a corresponding plurality of sensors. A plurality of regional groupings of neural populations is stored, with each one of the plurality of regional groupings encompassing a plurality of neural populations having a predefined relationship. An aggregated representation of cross-regional interactions between the neural populations across a selected plurality of the regional groupings is produced based on a selected subset of the interaction sets.