Inventors:
Scott D. Seiwert - Pacifica CA, US
Leonid Beigelman - San Mateo CA, US
Brad Buckman - Oakland CA, US
Antitsa Dimitrova Stoycheva - Half Moon Bay CA, US
Steven B. Porter - Mill Valley CA, US
Williamson Ziegler Bradford - Ross CA, US
Vladimir Serebryany - Burlingame CA, US
Assignee:
InterMune, Inc. - Brisbane CA
International Classification:
A61K 38/21, A61K 31/4709, A61K 31/7056, A61K 31/4738, A61K 31/407, A61K 31/4725, A61K 31/517, A61K 31/403, C07D 245/04, C07D 209/02
US Classification:
514 43, 514312, 514285, 514411, 514309, 5142662, 514336, 514365, 514414, 540460, 424 855, 424 857, 548465
Abstract:
The embodiments provide compounds of the general Formulae I, II, III, IV, V, VI, VII, and X, as well as compositions, including pharmaceutical compositions, comprising a subject compound. The embodiments further provide treatment methods, including methods of treating a hepatitis C virus infection and methods of treating liver fibrosis, the methods generally involving administering to an individual in need thereof an effective amount of a subject compound or composition.