STEVEN MARK LONESKY
Pharmacy in Collegeville, PA
License number
Pennsylvania RP037525L
Category
Pharmacy
Type
Pharmacist
Address
Address
Collegeville, PA 19473
Professional information
Orally Disintegrating Pharmaceutical Tablet Formulations Of Olanzapine
US Patent:
2006024, Oct 26, 2006
Filed:
Apr 11, 2006
Appl. No.:
11/402416
Inventors:
Shubha Chungi - Sharon MA, US
Claude Barnes - Quakertown PA, US
Steven Lonesky - Schwenksville PA, US
Claude Barnes - Quakertown PA, US
Steven Lonesky - Schwenksville PA, US
International Classification:
A61K 31/551, A61K 9/20
US Classification:
424464000, 514220000
Abstract:
This invention provides orally disintegrating pharmaceutical tablet formulations comprising per tablet the following ingredients in the following percentages by weight: olanzapine as an active ingredient in an amount from about 2.5% to about 10%; mannitol in an amount from about 75% to about 95%; a disintegrating agent in an amount from about 1.0% to about 10%; and one or more excipient in a total amount of about 0.1% to about 10%. This invention also provides a method of treating a patient in need of treatment with olanzapine which comprises administering to the patient a therapeutically effective dose of the above pharmaceutical tablet formulations. Finally, this invention provides a method of producing the above pharmaceutical tablet formulation which comprises combining the ingredients in the appropriate relative percentages by weight.