Inventors:
Csaba K. Zoltani - Lutherville MD, US
Gennady E. Platoff - Millersville MD, US
Steven I. Baskin - Bel Air MD, US
International Classification:
A61K 31/185, A61K 31/16, A61K 31/138, A61K 31/44, A61K 31/195, A61K 33/00, A61K 33/04, A61P 9/00, A61K 31/4375
US Classification:
424699, 514710, 514625, 514648, 514352, 514567, 424708, 424718, 514279
Abstract:
A method of treating a poison-caused pathology in an individual subject is described which includes administering a pharmaceutical composition including a therapeutically effective amount of a chloride current modulator, a therapeutically effective amount of an exogenous oxygen carrier, or a combination of a therapeutically effective amount of a chloride current modulator and a therapeutically effective amount of an exogenous oxygen carrier, to an individual subject exposed to a poison. Optionally, an inventive method further includes administering a therapeutic agent to inhibit poison-caused pathology. A composition according to the invention is described which includes a therapeutically effective amount of a chloride current modulator, a therapeutically effective amount of an exogenous oxygen carrier, or a combination of a therapeutically effective amount of a chloride current modulator and a therapeutically effective amount of an exogenous oxygen carrier. Further included in one embodiment is a therapeutic agent to inhibit poison-caused pathology.