STEVEN G KELSEN
Medical Practice in Meadowbrook, PA
License number
Pennsylvania MD013086E
Category
Medicine
Type
Medical Physician and Surgeon
Address
Address
Meadowbrook, PA 19046
Professional information
Biomarkers Of Chronic Obstructive Pulmonary Disease
US Patent:
2014003, Jan 30, 2014
Filed:
Mar 7, 2012
Appl. No.:
14/003120
Inventors:
Salim Merali - Bryn Mawr PA, US
Steven G. Kelsen - Rydal PA, US
Carlos A. Barrero - Philadelphia PA, US
Steven G. Kelsen - Rydal PA, US
Carlos A. Barrero - Philadelphia PA, US
Assignee:
TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION - Philadelphia PA
International Classification:
G01N 33/68
US Classification:
435 721, 435 23
Abstract:
The methods described herein are based on the discovery that the plasma level of a panel of specific proteins differs between two subject populations: 1) subjects at risk for chronic obstructive pulmonary disease (“COPD”) but not manifesting clinical symptoms of COPD; and 2) subjects having very severe COPD. The difference in plasma levels is statistically significant for each protein. The identification of these proteins thus facilitates susceptibility detection, early disease detection, disease severity assessment, disease progression monitoring, and therapy efficacy monitoring.