STEVEN D AVERBUCH
Medical Practice in North Wales, PA
License number
Pennsylvania MD060559L
Category
Medicine
Type
Medical Physician and Surgeon
Address
Address
North Wales, PA 19454
Professional information
Combination Methods Fo Saha And Targretin For Treating Cancer
US Patent:
2009022, Sep 10, 2009
Filed:
Aug 18, 2006
Appl. No.:
11/990724
Inventors:
Victoria M. Richon - Wellesley MA, US
Stanley R. Frankel - Yardley PA, US
Steven Averbuch - North Wales PA, US
Stanley R. Frankel - Yardley PA, US
Steven Averbuch - North Wales PA, US
International Classification:
A61K 31/216, A61K 31/192, A61P 35/00
US Classification:
514545, 514569
Abstract:
The present invention relates to a method of treating cancer in a subject in need thereof, by administering to a subject in need thereof a first amount of SAHA or a pharmaceutically acceptable salt or hydrate thereof, and a second amount of Targretin. The SAHA and Targretin may be administered to comprise therapeutically effective amounts.
Method Of Treating Cancers With Saha And Pemetrexed
US Patent:
2008026, Oct 30, 2008
Filed:
May 20, 2008
Appl. No.:
12/154089
Inventors:
James Pluda - Hatfield PA, US
Stanley R. Frankel - Yardley PA, US
Victoria M. Richon - Wellesley MA, US
Steven Averbuch - North Wales PA, US
Judy H. Chiao - Berkeley Heights NJ, US
Stanley R. Frankel - Yardley PA, US
Victoria M. Richon - Wellesley MA, US
Steven Averbuch - North Wales PA, US
Judy H. Chiao - Berkeley Heights NJ, US
International Classification:
A61K 31/56, A61K 31/519
US Classification:
514180, 5142651
Abstract:
The present invention relates to a method of treating cancer in a subject in need thereof, by administering to a subject in need thereof a first amount of a histone deacetylase (HDAC) inhibitor or a pharmaceutically acceptable salt or hydrate thereof, and a second amount of an anti-cancer agent. The HDAC inhibitor and the anti-cancer agent may be administered to comprise therapeutically effective amounts. In various aspects, the effect of the HDAC inhibitor and the anti-cancer agent may be additive or synergistic.
Method Of Treating Cancers With Saha And Pemetrexed
US Patent:
2007011, May 24, 2007
Filed:
Nov 3, 2006
Appl. No.:
11/592512
Inventors:
James Pluda - Hatfield PA, US
Stanley Frankel - Yardley PA, US
Victoria Richon - Wellesley MA, US
Steven Averbuch - North Wales PA, US
Judy Chiao - Berkeley Heights NJ, US
Stanley Frankel - Yardley PA, US
Victoria Richon - Wellesley MA, US
Steven Averbuch - North Wales PA, US
Judy Chiao - Berkeley Heights NJ, US
International Classification:
A61K 31/519, A61K 31/19
US Classification:
514265100, 514575000
Abstract:
The present invention relates to a method of treating cancer in a subject in need thereof, by administering to a subject in need thereof a first amount of a histone deacetylase (HDAC) inhibitor or a pharmaceutically acceptable salt or hydrate thereof, and a second amount of an anti-cancer agent. The HDAC inhibitor and the anti-cancer agent may be administered to comprise therapeutically effective amounts. In various aspects, the effect of the HDAC inhibitor and the anti-cancer agent may be additive or synergistic.