DR. STEPHEN RANDOLPH GROBMYER, MD
Radiology at Archer Rd, Gainesville, FL
License number
Florida ME97748
Category
Radiology
Type
Surgery
Address
Address
2
1600 SW Archer Rd, Gainesville, FL 32610
PO Box 918025, Orlando, FL 32891
PO Box 918025, Orlando, FL 32891
Phone
(352) 265-7973
(352) 265-7974 (Fax)
(352) 265-7974 (Fax)
Personal information
See more information about STEPHEN RANDOLPH GROBMYER at radaris.comName
Address
Phone
1200 Mossy Oak Dr, Inverness, FL 34450
Gainesville, FL
1710 Valdrario Blvd, Altamonte Springs, FL 32701
2150 7Th St, Gainesville, FL 32603
2150 7Th Ln, Gainesville, FL 32603
Professional information
Physician At University Of Florida
Position:
Physician at University of Florida
Location:
Gainesville, Florida Area
Industry:
Higher Education
Work:
University of Florida
since Jul 2004
-
Physician
Stephen Grobmyer, Cleveland OH
Specialties:
Surgery, Surgical Oncology
Work:
Cleveland Clinic Main Campus
9500 Euclid Ave, Cleveland, OH 44185 UF Surgical Specialties at Medical Plaza
2000 SW Archer Rd, Gainesville, FL 32608
9500 Euclid Ave, Cleveland, OH 44185 UF Surgical Specialties at Medical Plaza
2000 SW Archer Rd, Gainesville, FL 32608
Education:
The University of Texas Southwestern (1995) Surgery
Stephen Randolph Grobmyer, Gainesville FL
Specialties:
Surgeon
Address:
1600 Sw Archer Rd, Gainesville, FL 32610
Education:
Doctor of Medicine
Board certifications:
American Board of Surgery Certification in Surgery
Nir Materials And Nanomaterials For Theranostic Applications
US Patent:
2013003, Feb 14, 2013
Filed:
Feb 24, 2011
Appl. No.:
13/582242
Inventors:
Scott Chang Brown - Hockessin DE, US
Amit Kumar Singh - Gainesville FL, US
Parvesh Sharma - Gainesville FL, US
Brij M. Moudgil - Gainesville FL, US
Stephen R. Grobmyer - Gainesville FL, US
Amit Kumar Singh - Gainesville FL, US
Parvesh Sharma - Gainesville FL, US
Brij M. Moudgil - Gainesville FL, US
Stephen R. Grobmyer - Gainesville FL, US
Assignee:
University of Florida Research Foundation, Inc. - Gainesville FL
International Classification:
C07D 487/22, A61K 49/22, A61K 49/10, G01N 21/64, C01B 33/18, A61K 49/00, A61K 49/04, B82Y 40/00, B82Y 15/00
US Classification:
424 93, 540472, 424 91, 424 95, 424 96, 424 944, 436172, 423335, 977773, 977811, 977920, 977929, 977930, 977928, 977896
Abstract:
Novel fluorescent dye comprising metal oxide nanoparticles are prepared where the nanoparticles are as small as 3 nm or up to 7000 nm in diameter and where the dye is bound within the metal oxide matrix. In some embodiments the invention, novel dyes are covalently attached to the matrix and in other embodiments of the invention a dye is coordinate or ionic bound within the metal oxide matrix. A method for preparing the novel covalently bondable modified fluorescent dyes is presented. A method to prepare silica comprising nanoparticles that are 3 to 8 nm in diameter is presented. In some embodiments, the fluorescent dye comprising metal oxide nanoparticles are further decorated with functionality for use as multimodal in vitro or in vivo imaging agents. In other embodiments of the invention, the fluorescent dye comprising metal oxide nanoparticles provide therapeutic activity and incorporated therapeutic temperature monitoring.
Near-Ir Indocyanine Green Doped Multimodal Silica Nanoparticles And Methods For Making The Same
US Patent:
2013010, May 2, 2013
Filed:
Feb 24, 2011
Appl. No.:
13/582226
Inventors:
Parvesh Sharma - Gainesville FL, US
Scott Chang Brown - Hockessin DE, US
Niclas Bengtsson - Lake Forest Park WA, US
Glenn A. Walter - Newberry FL, US
Nobutaka Iwakuma - Kurume, JP
Edward W. Scott - Gainesville FL, US
Stephen R. Grobmyer - Gainesville FL, US
Swadeshmukul Santra - Orlando FL, US
Brij M. Moudgil - Gainesville FL, US
Scott Chang Brown - Hockessin DE, US
Niclas Bengtsson - Lake Forest Park WA, US
Glenn A. Walter - Newberry FL, US
Nobutaka Iwakuma - Kurume, JP
Edward W. Scott - Gainesville FL, US
Stephen R. Grobmyer - Gainesville FL, US
Swadeshmukul Santra - Orlando FL, US
Brij M. Moudgil - Gainesville FL, US
Assignee:
UNIVERSITY OF FLORIDA RESEARCH FOUNDATION INC. - GAINESVILLE FL
International Classification:
A61N 5/06, A61K 49/00, G01N 21/64
US Classification:
424 932, 436172, 424 96, 424490, 424 93, 604 20
Abstract:
The subject invention provides novel fluorescent core-shell nanoparticles comprising an encapsulated fluorescent core comprising an ionically bound fluorescent dye and a metal oxide shell. In one exemplary embodiment of the invention a core containing indocyanine green (ICG) with a silica shell that displays excellent photostability for generation of a near infrared fluorescence signal. The fluorescent core-shell nanoparticle can be further modified to act as an MRI, x-ray, or PAT contrast agent. The ICG nanoparticles can also be used as photodynamic therapeutic agent. Other embodiments of the invention directed to methods of making the novel core-shell nanoparticles and to the use of the core-shell nanoparticles for in vitro or in vivo imaging.
Targeted Cellular Selectivity Of Surface Active Molecules
US Patent:
2011002, Jan 27, 2011
Filed:
Feb 2, 2009
Appl. No.:
12/865589
Inventors:
Brij M. Moudgil - Gainesville FL, US
Manoj Varshney - Gainesville FL, US
Stephen R. Grobmyer - Gainesville FL, US
Manoj Varshney - Gainesville FL, US
Stephen R. Grobmyer - Gainesville FL, US
Assignee:
University of Florida Resarch Foundation, Inc. - Gainesville FL
International Classification:
A61K 49/00, A61K 31/765, A61K 31/20, A61K 31/201, A61K 31/23, A61K 31/231, A61K 36/47, A61K 36/889, A61K 36/899, A61K 31/341, A61K 31/08, A61K 31/355, A61K 31/7024, A61K 31/05, A61K 31/575, A61K 31/221, A61K 31/255, A61P 35/00
US Classification:
424 91, 424 7831, 514558, 514560, 514552, 424731, 424727, 424750, 514473, 424 7838, 514722, 514458, 514 23, 514731, 514182, 514551, 514517
Abstract:
A method for the treatment of cancer involves delivering a surface active agent to an organism, where the surface active agent selectively partitions to and kills cancer cells as opposed to healthy cells. The surface active agent can be an ionic or a non-ionic surfactant with a HLB of less than 29 or a mixture of surface active agents with a HLB of less than 40, where the hydrophobic portion is a lesser fraction of the surface active agent than the hydrophilic portion. A fluorescence method of detecting and locating cancer cells in an organism involves delivering a surface active agent, where the surface active agent includes a fluorescence moiety that upon selective partitioning of the surface active agent to the cancer cells and irradiation by a radiation source to excite the fluorescence moiety, a fluorescence emission is observed permitting the detection and location of the cancerous tissue by local volumes of relatively high intensity emission.
Use Of Fullerenes In Photoacoustic Imaging
US Patent:
2011005, Mar 3, 2011
Filed:
Oct 31, 2008
Appl. No.:
12/740884
Inventors:
Vijay Krishna - Gainesville FL, US
Brij M. Moudgil - Gainesville FL, US
Benjamin L. Koopman - Gainesville FL, US
Stephen Grobmyer - Gainesville FL, US
Qiang Wang - Gainesville FL, US
Qizhi Zhang - Gainesville FL, US
Huabei Jiang - Gainesville FL, US
Parvesh Sharma - Gainesville FL, US
Amit Kumar Singh - Gainesville FL, US
Brij M. Moudgil - Gainesville FL, US
Benjamin L. Koopman - Gainesville FL, US
Stephen Grobmyer - Gainesville FL, US
Qiang Wang - Gainesville FL, US
Qizhi Zhang - Gainesville FL, US
Huabei Jiang - Gainesville FL, US
Parvesh Sharma - Gainesville FL, US
Amit Kumar Singh - Gainesville FL, US
Assignee:
UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. - Gainesville FL
International Classification:
A61K 49/00, C12Q 1/02, H04B 1/02, G01S 15/89, B82Y 15/00, B82Y 5/00
US Classification:
424 91, 435 29, 367137, 367 87, 977734, 977927, 977953
Abstract:
Fullerenes, when irradiated with electromagnetic radiation, generate acoustic waves. A photoacoustic tomography method using a material comprising fullerenes is disclosed that includes irradiating the material with a radiation beam such as a laser. The resultant photoacoustic effect produced by the material is detected by at least one detector. A photoacoustic tomography system using a material comprising fullerenes is also described.
Multimodal Nanoparticles For Non-Invasive Bio-Imaging
US Patent:
2010025, Oct 7, 2010
Filed:
Aug 28, 2008
Appl. No.:
12/675633
Inventors:
Parvesh Sharma - Gainesville FL, US
Brij M. Moudgil - Gainesville FL, US
Glenn A. Walter - Newberry FL, US
Stephen R. Grobmyer - Gainesville FL, US
Swadeshmukul Santra - Orlando FL, US
Huabei Jiang - Gainesville FL, US
Scott Chang Brown - Gainesville FL, US
Edward W. Scott - Gainesville FL, US
Qizhi Zhang - Gainesville FL, US
Niclas Bengtsson - Gainesville FL, US
Brij M. Moudgil - Gainesville FL, US
Glenn A. Walter - Newberry FL, US
Stephen R. Grobmyer - Gainesville FL, US
Swadeshmukul Santra - Orlando FL, US
Huabei Jiang - Gainesville FL, US
Scott Chang Brown - Gainesville FL, US
Edward W. Scott - Gainesville FL, US
Qizhi Zhang - Gainesville FL, US
Niclas Bengtsson - Gainesville FL, US
Assignee:
UNIVERSITY OF FLORIDA RESEARCH FOUNDATION INC. - Gainesville FL
International Classification:
A61K 49/06, A61K 49/04
US Classification:
424 932, 424 942
Abstract:
Multimodal nanoparticles are nanoparticles containing contrast agents for PAT and one or more of luminescence imaging, x-ray imaging, and/or MRI. The multimodal nanoparticles can have a dielectric core comprising an oxide with a metal coating on the core. The particles can be metal speckled. The multimodal nanoparticles can be used for therapeutic purposes such as ablation of tumors or by neutron capture in addition to use as contrast agents for imaging.