STEPHEN R ASH, MD
Osteopathic Medicine at Salem St, Lafayette, IN

6409699, Jun 25, 2002

Jun 28, 1999

09/284904

Stephen R. Ash - Lafayette IN

Renal Solutions, Inc. - West Lafayette IN

A61M 100

604 29

The present invention relates generally to advantageous devices and methods for treating patients suffering from renal insufficiency and/or hepatic insufficiency. More particularly, the invention relates in certain aspects to devices and methods for performing continuous flow-through peritoneal dialysis (CFPD). In other aspects of the invention, peritoneal dialysis systems are provided which utilizes a bioreactor to regenerate peritoneal fluid for re-infusion into a peritoneal cavity. The invention, therefore, provides advantageous systems for passing fluid through a patients peritoneal cavity at a relatively high flow rate, while maintaining in the peritoneal cavity an optimal dialysate pressure, to thereby alter the contents of the patients blood by diffusion of molecules through the peritoneal membrane.

4387777, Jun 14, 1983

Oct 26, 1981

6/315246

Stephen R. Ash - LaFayette IN

Willo Partners - Aurora IL

G01G 2322, G01G 2314, G01G 300, G01G 118, G01G 2122

177 43

Caloric counting method and apparatus comprises a base support structure, a plate support structure pivotally mounted on the base support structure, and scale means connected to said plate support structure at a point remote from the pivot line thereof. A plate carrying a combination of food components constituting an entire meal is positioned on the plate support structure to determine the total caloric content of the entire meal. The plate is provided with indicia defining different zones on the plate for foods having different calories per gram, these zones being arranged so that the zone corresponding to foods having the least calories per gram is positioned nearest the pivotal mounting of the plate support structure when the plate is positioned thereon. The patient places the food components constituting an entire meal in the correct zones on the plate and the total caloric content of the entire meal is determined in a single operation by reading the scale which is calibrated in calories.

5906978, May 25, 1999

Jun 5, 1997

8/869331

Stephen R. Ash - Lafayette IN

Hemocleanse, Inc. - West Lafayette IN

A61K 3170, A61K 31295, A61K 3326

514 23

The invention relates to methods and compositions for delivering iron to an iron-deficient patient, more particularly, to methods whereby an iron complex comprising divalent or trivalent ionic iron complexed with one or more low molecular weight anions is administered to a patient by transfer from dialysate. A complex selected according to the invention is non-polymeric; soluble in an aqueous medium; chemically stable, thereby preventing the dissociation of iron ions from the anions under conditions according to the invention; and can be well absorbed into blood and the living body. Also provided are dialysate compositions including therein an iron complex selected according to the invention, and dialysate concentrates which may be diluted to yield an inventive dialysate composition.

4777953, Oct 18, 1988

Feb 25, 1987

7/018616

Stephen R. Ash - Lafayette IN

Ash Medical Systems, Inc. - West Lafayette IN

A61B 505

128635

A method and device for long term monitoring of the blood level of various blood constituents. The monitoring is accomplished by capillary filtration and collection of an ultrafiltrate of blood. Filtration of the ultrafiltrate occurs through a filter composed of hollow fibers which are implanted within an interstitial body space in fluid communication with blood capillaries. The ultrafiltrate is drawn through the filter and into an ultrafiltrate collector which extends externally of the body. The collector provides a vacuum for withdrawing the ultrafiltrate and holds discrete liquid samples of the ultrafiltrate. The method and device is particularly suited for long term monitoring of blood glucose levels in diabetic patients or other blood chemical constituents in other patients.

2008027, Nov 13, 2008

May 10, 2007

11/801616

Stephen R. Ash - Lafayette IN, US
Janusz Steczko - West Lafayette IN, US

A01N 25/34, A01N 33/02, A01N 43/26, A01N 43/84, A01P 1/00

424422, 514 12, 5142248, 514297, 514438, 514544, 514646

In general, this application is directed to medical devices that exhibit antimicrobial activity and to methods for preparing and using the medical devices. The medical devices of the present application include a polymeric portion that has been impregnated with a paraben and an organic dye in a manner whereby the paraben and organic dye exhibiting antibacterial properties. In one form, the paraben is impregnated into the polymeric portion before impregnation thereof with the organic dye. In another form, it is contemplated that the polymeric material may include methyl paraben, propyl paraben, and methylene blue. It is further contemplated that the polymeric material is effective in releasing at least one of the paraben and organic dye to prohibit bacterial growth in surrounding tissue and/or fluid.

2008014, Jun 26, 2008

Dec 22, 2006

11/644237

Stephen R. Ash - Lafayette IN, US

B01D 61/32

210646

The instant method involves intermittently infusing saline boluses into a patient's bloodstream during dialysis, and monitoring how long it takes for the bolus to complete a full circuit through the body. The concentrations versus time of one of more return flows as a result of the injected bolus are measured including a peak resulting from a fast circuit path, a peak resulting from a slow circuit path, and an average of the two aforementioned peaks. These parameters can be monitored over time in response to the injection of a plurality of boluses and their values over time used to determine the condition of the patient. Because of the rules governing abstracts, this abstract should not be used to construe the claims.

2004009, May 13, 2004

Jun 13, 2003

10/276035

Stephen Ash - Lafayette IN, US

A61M005/00

604/264000, 604/508000, 427/002100, 604/187000, 424/158100

This invention relates to compositions, methods and devices relating to the infusion of a catheter lock solution into an indwelling catheter. Inventive compositions, methods and devices aid in diminishing the effects of infection in the catheters and occlusion of the catheters. An inventive lock solution includes an anticoagulant and a photo-oxidant, and preferably has a density suitable for retention of the solution in a catheter during the lock period.

4581141, Apr 8, 1986

Apr 5, 1983

6/482210

Stephen R. Ash - Lafayette IN

Purdue Research Foundation - West Lafayette IN

B01D 1300

210502

Compositions for removing uremic substances during hemodialysis comprising an aqueous slurry containing charcoal, a highly calcium-loaded zeolite cation exchanger, purified urease (which may be bound to a portion of the zeolite, a suspending agent, and optionally an aliphatic carboxylic acid resin in the H. sup. + form, and a hemodialysis method employing such compositions.

2013029, Nov 7, 2013

May 1, 2012

13/461452

Stephen R. Ash - Lafayette IN, US

MERIT MEDICAL SYSTEMS, INC. - South Jordan UT

A61M 25/14, A61M 1/28

604 28, 604246, 604247

A catheter configured with an elongate tube and a diffuser is disclosed. The diffuser may be configured to facilitate high flow rates through the catheter and to resist blockage of openings disposed within the body. Further, the catheter may be comprised of flexible materials to facilitate delivery into and removal from the body. In some embodiments the diffuser may be generally disc shaped.

7947179, May 24, 2011

Jun 30, 2010

12/827617

Benjamin P. Rosenbaum - Nashville TN, US
Stephen R. Ash - Lafayette IN, US
David J. Carr - West Lafayette IN, US

Renal Solutions, Inc. - Warrendale PA

B01D 61/34

210638, 210 962, 210130, 210259, 210266, 210645, 210646

A dialysate fluid circulation apparatus includes a dialyzer, a first housing and a second housing. The first housing contains material capable of releasing sodium into dialysate fluid flowing through the first housing. The second housing contains material capable of binding sodium ions from dialysate fluid flowing through the second housing. Hydraulic conduit sections are configured to extend between the dialyzer, the first housing, and the second housing to connect the dialyzer with the housings in a primary flow path for dialysate fluid to flow from the dialyzer to the first housing, from the first housing to the second housing, and from the second housing back to the dialyzer.