STEPHEN M ANSELL, M.D.
Osteopathic Medicine at 1 St, Rochester, MN

License number
Minnesota 38954
Category
Osteopathic Medicine
Type
Hematology
Address
Address
200 1St St SW, Rochester, MN 55905
Phone
(507) 284-2511

Professional information

Stephen M Ansell Photo 1

Dr. Stephen M Ansell, Rochester MN - MD (Doctor of Medicine)

Specialties:
Hematology, Medical Oncology, Oncology
Address:
Mayo Clinic
200 1St St SW, Rochester 55905
(507) 284-2511 (Phone)
Certifications:
Hematology, 2008, Internal Medicine, 1996, Medical Oncology, 1999
Awards:
Healthgrades Honor Roll
Languages:
English
Hospitals:
Mayo Clinic
200 1St St SW, Rochester 55905
Mayo Clinic Saint Marys Hospital
1216 2Nd St South #West, Rochester 55902
North Memorial Medical Center
3300 Oakdale Ave North, Robbinsdale 55422
Education:
Medical School
University of Pretoria / Faculty of Medicine
Coronation Hospital
Graduated: 1987
Mayo Grad School Med
Graduated: 1996


Stephen M Ansell Photo 2

Stephen M Ansell, Rochester MN

Specialties:
Hematologist
Address:
200 1St St Sw, Rochester, MN 55905
Education:
University of Pretoria, School of Medicine - Bachelor of Medicine, Bachelor of Surgery
Doctor of Medicine
The Mayo Clinic - Fellowship - Hematology and Oncology (Internal Medicine)
The Mayo Clinic - Residency - Internal Medicine
Board certifications:
American Board of Internal Medicine Certification in Internal Medicine, American Board of Internal Medicine Sub-certificate in Hematology (Internal Medicine), American Board of Internal Medicine Sub-certificate in Oncology (Internal Medicine)


Stephen Ansell Photo 3

Promoter Polymorphisms Of The Blys Gene And Use In Diagnostic Methods

US Patent:
2007020, Sep 6, 2007
Filed:
Nov 1, 2006
Appl. No.:
11/555559
Inventors:
Stephen Ansell - Rochester MN, US
Anne Novak - Oronoco MN, US
International Classification:
C12Q 1/68, C12M 3/00
US Classification:
435006000, 435287200
Abstract:
The present invention provides an isolated polynucleotide comprising at least one polymorphic nucleotide sequence, for example, at position −871 from the promoter region of the BLyS gene, and diagnostic assays for detecting the presence of this polymorphism associated with a condition associated with BLyS activity, such as hematological malignancy including B cell malignancies. The diagnostic assays are useful in predicting an individual's likelihood of developing a condition associated with BLyS activity, such as hematological malignancies, and for methods for treating an individual clinically diagnosed with a condition associated with BLyS activity, such as prediction of a patient's likelihood to respond to a specific drug treatment. The invention also provides an array of nucleic acid molecules immobilized on a solid surface, where at least one of the nucleic acid molecules comprises a BLyS polymorphic nucleic acid molecule. The nucleic acid arrays of the invention allow rapid detection of hybridizing nucleic acid-molecules, in a nucleic acid sample from an individual, of a BLyS polymorphism associated with hematological malignancy.


Stephen Ansell Photo 4

Methods For Treating B-Cell Malignancies Using A Taci-Ig Fusion Molecule

US Patent:
7842292, Nov 30, 2010
Filed:
Aug 9, 2006
Appl. No.:
11/502134
Inventors:
Herve Broly - Saint Selve, FR
Arnaud Ythier - Collex-Bossy, CH
Eric Sievers - Seattle WA, US
Sharon J. Busby - Seattle WA, US
Jan Öhrström - Mercer Island WA, US
Ivan Nestorov - Issaquah WA, US
Stephen M. Ansell - Rochester MN, US
Assignee:
Ares Trading S.A.
Zymogenetics, Inc. - Seattle WA
Mayo Foundation for Medical Education and Research - Rochester MN
International Classification:
A61K 39/395
US Classification:
4241331, 4241551
Abstract:
The present invention provides methods and compositions for treatment of B-cell malignancies, including non-Hodgkin's lymphoma, comprising administering to a patient in need of the treatment a TACI-Ig fusion molecule in amount sufficient to suppress proliferation-inducing functions of BlyS and APRIL.


Stephen Ansell Photo 5

Polymorphisms Of The Blys Gene And Use In Diagnostic Methods

US Patent:
8003325, Aug 23, 2011
Filed:
Nov 26, 2008
Appl. No.:
12/323861
Inventors:
Stephen M. Ansell - Rochester MN, US
Anne J. Novak - Oronoco MN, US
Assignee:
Mayo Foundation for Medical Education and Research - Rochester MN
International Classification:
C12Q 1/68, C12P 19/34, C07H 21/02, C07H 21/04
US Classification:
435 6, 435 912, 536 231, 536 243
Abstract:
The present invention provides an isolated polynucleotide comprising at least one polymorphic nucleotide sequence, for example, the major alleles of the SNPs described as rs12583006, rs1224141, and rs1248930 and diagnostic assays for detecting the presence of these polymorphism associated with a condition associated with BLyS activity, such as hematological malignancy including B cell malignancies. The diagnostic assays are useful in predicting an individual's likelihood of developing a condition associated with BLyS activity, such as hematological malignancies, and for methods for treating an individual clinically diagnosed with a condition associated with BLyS activity, such as prediction of a patient's likelihood to respond to a specific drug treatment. The invention also provides an array of nucleic acid molecules immobilized on a solid surface, where at least one of the nucleic acid molecules comprises a BLyS polymorphic nucleic acid molecule. The nucleic acid arrays of the invention allow rapid detection of hybridizing nucleic acid-molecules, in a nucleic acid sample from an individual, of a BLyS polymorphism associated with hematological malignancy.


Stephen Ansell Photo 6

System And Method For Assessing Response To Chemotherapy Using Magnetic Resonance Elastography

US Patent:
2012013, May 24, 2012
Filed:
Nov 21, 2011
Appl. No.:
13/301300
Inventors:
Kiaran P. McGee - Rochester MN, US
Richard L. Ehman - Rochester MN, US
Stephen M. Ansell - Rochester MN, US
Yogesh K. Mariappan - Rochester MN, US
Jun Chen - Rochester MN, US
International Classification:
A61B 5/055
US Classification:
600411
Abstract:
A system and method for determining a response of a tumor following a chemotherapy process includes the use of a magnetic resonance elastography (MRE) driver and a magnetic resonance imaging (MRI) system. The method includes controlling the MRE driver and the MRI system to acquire raw MRE data from the tumor, inverting the raw MRE data to produce an elastogram of the tumor, and determining a response of the tumor to the chemotherapy process from the elastogram.


Stephen Ansell Photo 7

Improving Treatments

US Patent:
2007028, Dec 13, 2007
Filed:
Aug 2, 2005
Appl. No.:
11/573165
Inventors:
William Sandborn - Rochester MN, US
William Faubion - Oronoco MN, US
Stephen Ansell - Rochester MN, US
Assignee:
MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH - Rochester MN
International Classification:
A61K 39/395
US Classification:
424131100, 424144100, 424178100
Abstract:
Methods and materials for reducing a mammal's ability to produce antibodies against an antigen (e.g., a therapeutic polypeptide) to be administered to the mammal are provided herein.