STEPHEN A BLACK
Nursing at Shirley Dr, Concord, CA
License number
Florida 1007502
Issued Date
Sep 11, 1978
Effective Date
Aug 30, 2000
Expiration Date
Jul 31, 1998
Category
Health Care
Type
Registered Nurse
Address
Address
1600 Shirley Dr, Concord, CA 94523
Professional information
Cholesterol Disposal Fusion Enzymes
US Patent:
5939318, Aug 17, 1999
Filed:
Feb 5, 1996
Appl. No.:
8/564090
Inventors:
Walter L. Miller - San Francisco CA
Jennifer A. Harikrishna - Kuala Lumpur, MY
Stephen M. Black - Concord CA
Jennifer A. Harikrishna - Kuala Lumpur, MY
Stephen M. Black - Concord CA
Assignee:
Regents of the University of California - Oakland CA
International Classification:
C12N 510, C12N 121, C12N 1562, C12N 1579
US Classification:
435325
Abstract:
Fusion enzymes having multiple segments of different biological activity including one segment having P450scc activity and at least one segment having electron-transfer activity for transferring electrons to P450scc are described along with genetic constructs for production of such enzymes and methods for their use. Methods for their use include cholesterol degradation in vitro or in vivo as well as conversion of cholesterol to other useful steroidal products including pregnenolone.