DR. STEPHAN R TARGAN, M.D.
Osteopathic Medicine at Beverly Blvd, Los Angeles, CA
License number
California G22752
Category
Osteopathic Medicine
Type
Internal Medicine
License number
California G22752
Category
Osteopathic Medicine
Type
Infectious Disease
License number
California G22752
Category
Osteopathic Medicine
Type
Gastroenterology
Address
Address
8700 Beverly Blvd, Los Angeles, CA 90048
Phone
(310) 423-4100
(310) 423-0146 (Fax)
(310) 423-0146 (Fax)
Personal information
See more information about STEPHAN R TARGAN at radaris.comName
Address
Phone
240 22Nd St, Santa Monica, CA 90402
240 22Nd St, Santa Monica, CA 90402
240 22Nd St, Santa Monica, CA 90402
Professional information
Stephan Raoul Targan, West Hollywood CA
Specialties:
Internal Medicine, Gastroenterology, Infectious Disease
Work:
Cedars-Sinai Medical Center
8700 Beverly Blvd, Los Angeles, CA 90048 Cedars-Sinai Medical Center
8730 Alden Dr, Los Angeles, CA 90048
8700 Beverly Blvd, Los Angeles, CA 90048 Cedars-Sinai Medical Center
8730 Alden Dr, Los Angeles, CA 90048
Education:
Johns Hopkins University (1971)
Methods Of Screening For Crohns Disease Using Tnf Microsatellite Alleles
US Patent:
6534263, Mar 18, 2003
Filed:
Oct 15, 1999
Appl. No.:
09/419406
Inventors:
Scott E. Plevy - Pacific Palisades CA
Jerome I. Rotter - Los Angeles CA
Stephan R. Targan - Los Angeles CA
Hiroo Toyoda - Arcadia CA
Huiying Yang - Cerritos CA
Jerome I. Rotter - Los Angeles CA
Stephan R. Targan - Los Angeles CA
Hiroo Toyoda - Arcadia CA
Huiying Yang - Cerritos CA
Assignee:
Cedars-Sinai Medical Center - Los Angeles CA
International Classification:
C12Q 1568
US Classification:
435 6, 435 912, 536 231, 536 235, 536 2431, 536 2433
Abstract:
A novel association between certain tumor necrosis factor microsatellite alleles and Crohns disease has been discovered. In accordance with the present invention, there is provided methods for screening for Crohns disease comprising detecting the presence or absence of nucleic acid of a subject encoding TNF microsatellite alleles associated with Crohns disease, wherein the presence of nucleic acid encoding three or more of the alleles is indicative of Crohns disease. Kits useful for screening for Crohns disease are also provided which comprise nucleic acid encoding TNF microsatellite alleles associated with Crohns disease.
Methods Of Diagnosing A Clinical Subtype Of Crohn's Disease With Features Of Ulcerative Colitis
US Patent:
5874233, Feb 23, 1999
Filed:
Aug 15, 1996
Appl. No.:
8/689870
Inventors:
Stephan R. Targan - Los Angeles CA
Eric A. Vasiliauskas - Hermosa Beach CA
Scott E. Plevy - Pacific Palisades CA
Eric A. Vasiliauskas - Hermosa Beach CA
Scott E. Plevy - Pacific Palisades CA
Assignee:
Cedars-Sinai Medical Center - Los Angeles CA
International Classification:
G01N 33543, G01N 33564
US Classification:
435 724
Abstract:
The present invention provides a method of diagnosing a clinical subtype of Crohn's disease (CD) by determining whether perinuclear anti-neutrophil antibodies (pANCA) are present in a patient with CD, where the presence of pANCA indicates the clinical subtype of CD with features of ulcerative colitis (UC). The invention also provides a method of diagnosing a clinical subtype of CD by detecting an Arg. sup. 241 allele at an ICAM-1 locus in a patient with CD, where the Arg. sup. 241 allele indicates a clinical subtype of CD with features of ulcerative colitis. In addition, the invention provides a method of diagnosing a pANCA-positive subtype of CD by detecting an Arg. sup. 241 allele at an ICAM-1 locus in a patient with CD, where the Arg. sup. 241 allele indicates the pANCA-positive subtype of CD.
Methods For Selectively Detecting Perinuclear Anti-Neutrophil Cytoplasmic Antibody Of Ulcerative Colitis Or Primary Sclerosing Cholangitis
US Patent:
5750355, May 12, 1998
Filed:
Oct 7, 1994
Appl. No.:
8/320163
Inventors:
Stephan R. Targan - Los Angeles CA
Alda Vidrich - Pacific Palisades CA
Alda Vidrich - Pacific Palisades CA
Assignee:
Cedars-Sinai Medical Center - Los Angeles CA
International Classification:
G01N 3353, G01N 33555, G01N 33567
US Classification:
435 724
Abstract:
The invention is directed to methods and kits for detecting and measuring the presence or absence of perinuclear anti-neutrophil cytoplasmic autoantibody of ulcerative colitis or primary sclerosing cholangitis. The methods and kits of the present invention provide safe and reliable means for diagnosing ulcerative colitis and primary sclerosing cholangitis. The antigens reactive with perinuclear anti-neutrophil cytoplasmic autoantibody of ulcerative colitis and primary sclerosing cholangitis are also provided.
Methods For Selectively Detecting Perinuclear Anti-Neutrophil Cytoplasmic Antibody Of Ulcerative Colitis, Primary Sclerosing Cholangitis, Or Type 1 Autoimmune Hepatitis
US Patent:
5830675, Nov 3, 1998
Filed:
Jun 7, 1995
Appl. No.:
8/480753
Inventors:
Stephan R. Targan - Los Angeles CA
Alda Vidrich - Pacific Palisades CA
Alda Vidrich - Pacific Palisades CA
Assignee:
Cedars-Sinai Medical Center - Los Angeles CA
International Classification:
G01N 3353, G01N 33555, G01N 33567
US Classification:
435 724
Abstract:
The invention is directed to methods and kits for detecting and measuring the presence or absence of perinuclear anti-neutrophil cytoplasmic antibody of ulcerative colitis, primary sclerosing cholangitis or type 1 autoimmune hepatitis. The methods and kits of the present invention provide safe and reliable means for diagnosing ulcerative colitis, primary sclerosing cholangitis, and type 1 autoimmune hepatitis. The antigens reactive with perinuclear anti-neutrophil cytoplasmic autoantibody of ulcerative colitis and primary sclerosing cholangitis are also provided.
Methods Of Diagnosing Ulcerative Colitis And Crohn's Disease
US Patent:
5681699, Oct 28, 1997
Filed:
Feb 11, 1994
Appl. No.:
8/196003
Inventors:
Jerome I. Rotter - Los Angeles CA
Stephan R. Targan - Los Angeles CA
Huiying Yang - Cerritos CA
Arthur L. Beaudet - Houston TX
Devendra Vora - Torrance CA
Stephan R. Targan - Los Angeles CA
Huiying Yang - Cerritos CA
Arthur L. Beaudet - Houston TX
Devendra Vora - Torrance CA
Assignee:
Cedars-Sinai Medical Center - Los Angeles CA
International Classification:
C12Q 168, C07H 2102, C07H 2104
US Classification:
435 6
Abstract:
A novel association between IBD and a polymorphism at amino acid residue 241 of ICAM-1 has been discovered. In accordance with the present invention there is provided methods of screening for IBD, methods for treating IBD, antibodies specifically reactive wish ICAM-1 encoded by R241 allele and kits which exploit the inventive methods.
Methods Of Screening For Ulcerative Colitis And Crohn's Disease By Detecting Vh3-15 Autoantibody And Panca
US Patent:
5691151, Nov 25, 1997
Filed:
Oct 7, 1994
Appl. No.:
8/320515
Inventors:
Jonathan Braun - Encino CA
Stephan R. Targan - Los Angeles CA
Stephan R. Targan - Los Angeles CA
Assignee:
Regents of University of California - Oakland CA
International Classification:
G01N 33564
US Classification:
435 72
Abstract:
The present invention provides novel methods of screening for ulcerative colitis and Crohn's disease which include the detection of two disparate autoantibodies: pANCA and VH3-15 autoantibody. The present invention also provides kits for screening ulcerative colitis and Crohn's disease.
Methods Of Screening For Crohn's Disease Using Tnf Microsatellite Alleles
US Patent:
6001569, Dec 14, 1999
Filed:
Feb 11, 1997
Appl. No.:
8/798668
Inventors:
Scott E. Plevy - Pacific Palisades CA
Jerome I. Rotter - Los Angeles CA
Stephan R. Targan - Los Angeles CA
Hiroo Toyoda - Arcadia CA
Huiying Yang - Cerritos CA
Jerome I. Rotter - Los Angeles CA
Stephan R. Targan - Los Angeles CA
Hiroo Toyoda - Arcadia CA
Huiying Yang - Cerritos CA
Assignee:
Cedars-Sinai Medical Center - Los Angeles CA
International Classification:
C12Q 168, C07H 2104, C12P 1934
US Classification:
435 6
Abstract:
A novel association between certain tumor necrosis factor microsatellite alleles and Crohn's disease has been discovered. In accordance with the present invention, there is provided methods for screening for Crohn's disease comprising detecting the presence or absence of nucleic acid of a subject encoding TNF microsatellite alleles associated with Crohn's disease, wherein the presence of nucleic acid encoding three or more of the alleles is indicative of Crohn's disease. Kits useful for screening for Crohn's disease are also provided which comprise nucleic acid encoding TNF microsatellite alleles associated with Crohn's disease.
Methods Of Screening For Ulcerative Colitis And Crohn's Disease
US Patent:
6884590, Apr 26, 2005
Filed:
Oct 15, 1999
Appl. No.:
09/419408
Inventors:
Jerome I. Rotter - Los Angeles CA, US
Stephan R. Targan - Los Angeles CA, US
Huiying Yang - Cerritos CA, US
Arthur L. Beaudet - Houston TX, US
Devendra Vora - Torrance CA, US
Stephan R. Targan - Los Angeles CA, US
Huiying Yang - Cerritos CA, US
Arthur L. Beaudet - Houston TX, US
Devendra Vora - Torrance CA, US
Assignee:
Cedars-Sinai Medical Center - Los Angeles CA
International Classification:
G01N033/53
US Classification:
435 71, 435 6, 435 72, 5303871, 536 235
Abstract:
A novel association between IBD and a polymorphism at amino acid residue 241 of ICAM-1 has been discovered. In accordance with the present invention there is provided methods of screening for IBD, methods for treating IBD, antibodies specifically reactive with ICAM-1 encoded by, R241 allele and kits which exploit the inventive methods.
Methods Of Screening For Ulcerative Colitis And Crohn's Disease
US Patent:
6008335, Dec 28, 1999
Filed:
Sep 19, 1997
Appl. No.:
8/933824
Inventors:
Jerome I. Rotter - Los Angeles CA
Stephan R. Targan - Los Angeles CA
Huiying Yang - Cerritos CA
Arthur L. Beaudet - Houston TX
Devendra Vora - Torrance CA
Stephan R. Targan - Los Angeles CA
Huiying Yang - Cerritos CA
Arthur L. Beaudet - Houston TX
Devendra Vora - Torrance CA
Assignee:
Cedars-Sinai Medical Center - Los Angeles CA
International Classification:
C07H 2102, C07H 2104, C12Q 168
US Classification:
536 231
Abstract:
A novel association between IBD and a polymorphism at amino acid residue 241 of ICAM-1 has been discovered. In accordance with the present invention there is provided methods of screening for IBD, methods for treating IBD, antibodies specifically reactive with ICAM-1 encoded by R241 allele and kits which exploit the inventive methods.