Inventors:
Kamehameha Wong - Sierra Madre CA, US
Saswati Chatterjee - Sierra Madre CA, US
Joel Conrad - Claremont CA, US
Stella Kim - San Diego CA, US
International Classification:
C12Q001/70, C07H021/04, C07K014/16
US Classification:
435005000, 435069300, 435320100, 435325000, 530350000, 536023200, 424192100
Abstract:
This invention pertains to methods for promoting stable and site-specific integration of rep deleted recombinant adeno-associated virus vectors which result in less variable transgene expression and increased safety. These vectors are useful for delivery of a functional gene product to the desired intracellular location.