Inventors:
Raymond Warrell - Westfield NJ, US
Stefan Grant - New York NY, US
Bob Brown - Long Hill Township NJ, US
International Classification:
A61K 39/395, A61K 38/21, A61K 38/20, A61K 38/17, A61K 31/454, A61K 31/203, A61K 33/36, A61K 33/24, A61K 31/553
US Classification:
424155100, 424617000, 424085200, 424085700, 514044000, 514012000, 514323000, 514559000, 424623000
Abstract:
The present invention relates to a combination of a pharmaceutical composition comprising a gallium compound, especially gallium nitrate, and one or more nonchemotherapeutic anticancer agents (NCAA) including antibodies, antisense molecules, anti-telomerase agents, aptamers, biologic response modifiers, bisphosphonates, cytotoxic fusion proteins, immunomodulatory agents, immunostimulatory agents, molecular decoys, molecular inhibitors, proteasome inhibitors, protein kinase inhibitors, retinoids, transcription factors and arsenic compounds, for the treatment of neoplasic disease in a mammal in need of treatment thereof.