Inventors:
Ziad Mallat - Paris, FR
Alain Tedgui - Paris, FR
Sotirios Tsimikas - La Jolla CA, US
Joseph Witztum - La Jolla CA, US
Assignee:
Institut National de la Sante et de la Recherche Medicale (INSERM) - Paris
The Regents of the University of California - Oakland CA
International Classification:
G01N 33/53
Abstract:
The present invention related to a method of identifying a subject having or at risk of having or developing a cardiovascular disease and/or a cardiovascular event, comprising: —measuring, in a sample obtained from said subject, at least two cardiovascular risk factors: a) sPLA2 type HA mass and b) oxidized phospholipids on apolipoprotein B-IOO particles (OxPL/apoB), —combining said measurements, the combined value of sPLA2 type HA mass and OxPL/apoB being indicative of having or a risk of having or developing a cardiovascular disease and/or cardiovascular event.