Inventors:
Steven D. MUNGER - Baltimore MD, US
Nanette I. Steinle - Millersville MD, US
Alan R. Shuldiner - Columbia MD, US
Soren Snitker - Baltimore MD, US
Cedrick D. Dotson - Baltimore MD, US
Amanda E.T. Elson - Baltimore MD, US
Stephen Vigues - Baltimore MD, US
Assignee:
University of Maryland - Baltimore MD
International Classification:
C12Q 1/68, C12N 5/02
Abstract:
The present invention relates to methods of determining an increased risk of a subject to acquire a trait of an obesity disorder or an obesity disorder, with the method comprising determining the genetic sequence of at least one taste receptor gene in the subject and reviewing the test genetic sequence(s) for the presence of at least one risk allele associated with at least one taste receptor. The presence of at least one difference in the test genetic sequence(s) and the presence of a risk allele associated with the taste receptor(s) may indicate an increased risk of the subject acquiring a trait of an obesity disorder or an obesity disorder.