Inventors:
Soner Altiok - Tampa FL, US
Assignee:
H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. - Tampa FL
International Classification:
A61K 49/00
US Classification:
800 3, 800 10, 435 29, 435 611
Abstract:
The subject invention pertains to a non-human animal model of human cancer, methods of producing a non-human animal model of human cancer, methods of using a non-human animal model to propagate human cancer cells, methods of using a non-human animal model to study cancer, methods of using a non-human animal model to screen potential treatments for a subject's cancer, methods of using a non-human animal model for treating cancer in a subject (providing personalized therapy), methods of using a non-human animal model for identifying a biomarker of cancer treatment; and methods of using a non-human animal model for selecting cancer patients for a clinical trial.