SIMON S JONES
Broker in Somerville, MA
License number
Massachusetts 9034518
Issued Date
Mar 18, 2000
Expiration Date
Nov 5, 2002
Type
Salesperson
Address
Address
Somerville, MA 02143
Professional information
Calcium Independent Cytosolic Phospholipase A2/B Enzymes
US Patent:
6645736, Nov 11, 2003
Filed:
Aug 9, 2001
Appl. No.:
09/927180
Inventors:
Simon Jones - Somerville MA
Jin Tang - Canton MA
Jin Tang - Canton MA
Assignee:
Genetics Institute, LLC - Cambridge MA
International Classification:
C12Q 134
US Classification:
435 18, 435198, 4352523, 4353201, 435 692, 435530, 435300, 435350, 435536, 435 232
Abstract:
The invention provides a novel calcium-independent cytosolic phospholipase A /B enzyme, polynucleotides encoding such enzyme and methods for screening unknown compounds for anti-inflammatory activity mediated by the arachidonic acid cascade.
Calcium Independent Cytosolic Phospholipase A.sub.2 /B Enzymes
US Patent:
5589170, Dec 31, 1996
Filed:
Apr 14, 1995
Appl. No.:
8/422106
Inventors:
Simon Jones - Somerville MA
Jin Tang - Canton MA
Jin Tang - Canton MA
Assignee:
Genetics Institute, Inc. - Cambridge MA
International Classification:
A61K 3846, C12N 920, C07H 2104
US Classification:
424 946
Abstract:
The invention provides a novel calcium-independent cytosolic phospholipase A. sub. 2 /B enzyme, polynucleotides encoding such enzyme and methods for screening unknown compounds for anti-inflammatory activity mediated by the arachidonic acid cascade.
Recombinant Erythropoietin Receptor Protein
US Patent:
5378808, Jan 3, 1995
Filed:
Jun 10, 1993
Appl. No.:
8/075069
Inventors:
Alan D'Andrea - Winchester MA
Gordon G. Wong - Brookline MA
Simon S. Jones - Somerville MA
Gordon G. Wong - Brookline MA
Simon S. Jones - Somerville MA
Assignee:
Genetics Institute, Inc. - Cambridge MA
International Classification:
C07K 1300
US Classification:
530350
Abstract:
The invention described encompasses an isolated DNA sequence encoding all or a portion thereof of a cell surface receptor murine and human erythropoietin (hereinafter EPO-R), along with the isolated polypeptide expressed by the DNA sequence (i. e. , isolated EPO-R). The invention also encompasses host cells containing the above-described DNA sequence, preferably, host cells which express the polypeptide encoded by the DNA sequence (EPO-R) at a significantly higher level than that produced by normal red blood cell precursors. The invention further encompasses DNA sequences encoding secreted forms of the human EPO-R and polypeptides corresponding thereto. The EPO-receptor in all of the disclosed forms can be used as models for designing drugs or in pharmaceutical compositions for treating anemias.
Calcium Independent Cytosolic Phospholipase A.sub.2 /B Enzymes
US Patent:
5554511, Sep 10, 1996
Filed:
Apr 14, 1995
Appl. No.:
8/422420
Inventors:
Simon Jones - Somerville MA
Jin Tang - Canton MA
Jin Tang - Canton MA
Assignee:
Genetics Institute, Inc. - Cambridge MA
International Classification:
C12P 2106, A61K 3846, C12N 920
US Classification:
435 691
Abstract:
The invention provides a novel calcium-independent cytosolic phospholipase A. sub. 2 /B enzyme, polynucleotides encoding such enzyme and methods for screening unknown compounds for anti-inflammatory activity mediated by the arachidonic acid cascade.
Antibodies To Calcium Independent Cytosolic Phospholipase A/B Enzymes
US Patent:
7112325, Sep 26, 2006
Filed:
Jul 1, 2003
Appl. No.:
10/612668
Inventors:
Simon Jones - Somerville MA, US
Jin Tang - Canton MA, US
Jin Tang - Canton MA, US
Assignee:
Genetics Institute, LLC - Cambridge MA
International Classification:
A61K 39/395
US Classification:
4241391, 4241411, 4241461, 5303879, 53038826
Abstract:
The invention provides a novel calcium-independent cytosolic phospholipase A/B enzyme, polynucleotides encoding such enzyme, antibodies to such enzyme, and methods for screening unknown compounds for anti-inflammatory activity mediated by the arachidonic acid cascade.
Methods Comprising Calcium Independent Cytosolic Phospholipase A/B Enzymes
US Patent:
5840511, Nov 24, 1998
Filed:
Oct 23, 1996
Appl. No.:
8/735716
Inventors:
Simon Jones - Somerville MA
Jin Tang - Canton MA
Jin Tang - Canton MA
Assignee:
Genetics Institute, Inc. - Cambridge MA
International Classification:
C12Q 144, A61K 3846
US Classification:
435 19
Abstract:
The invention provides a novel calcium-independent cytosolic phospholipase A. sub. 2 /B enzyme, polynucleotides encoding such enzyme and methods for screening unknown compounds for anti-inflammatory activity mediated by the arachidonic acid cascade.
Calcium Independent Cytosolic Phospholipase A/B Enzymes
US Patent:
7569669, Aug 4, 2009
Filed:
Jul 6, 2006
Appl. No.:
11/483146
Inventors:
Simon Jones - Somerville MA, US
Jin Tang - Canton MA, US
Jin Tang - Canton MA, US
Assignee:
Genetics Institute, LLC - Cambridge MA
International Classification:
C07K 1/00
US Classification:
530350, 536 231, 53038826
Abstract:
The invention provides a novel calcium-independent cytosolic phospholipase A/B enzyme, polynucleotides encoding such enzyme and methods for screening unknown compounds for anti-inflammatory activity mediated by the arachidonic acid cascade.
Calcium Independent Cytosolic Phospholipase A.sub.2 /B Enzymes
US Patent:
5976854, Nov 2, 1999
Filed:
Nov 8, 1995
Appl. No.:
8/555568
Inventors:
Simon Jones - Somerville MA
Jin Tang - Canton MA
Jin Tang - Canton MA
Assignee:
Genetics Institute, Inc. - Cambridge MA
International Classification:
C12N 920, C12N 510, C12N 1563, C07H 2104
US Classification:
435198
Abstract:
The invention provides a novel calcium-independent cytosolic phospholipase A. sub. 2 /B enzyme, polynucleotides encoding such enzyme and methods for screening unknown compounds for anti-inflammatory activity mediated by the arachidonic acid cascade.
Calcium Independent Cytosolic Phospholipase A2/B Enzymes
US Patent:
6274140, Aug 14, 2001
Filed:
Mar 6, 2000
Appl. No.:
9/519223
Inventors:
Simon Jones - Somerville MA
Jin Tang - Canton MA
Jin Tang - Canton MA
Assignee:
Genetics Institute, Inc.
International Classification:
A61K 3846, C12N 920, C12N 120, C12N 1500, C07H 2104
US Classification:
424 946
Abstract:
The invention provides a novel calcium-independent cytosolic phospholipase A. sub. 2 /B enzyme, polynucleotides encoding the enzyme and methods for screening unknown compounds for anti-inflammatory activity mediated by the arachidonic acid cascade.
Calcium Independent Cytosolic Phospholipase A2/B Enzymes
US Patent:
5466595, Nov 14, 1995
Filed:
Jul 27, 1994
Appl. No.:
8/281193
Inventors:
Simon Jones - Somerville MA
Jin Tang - Canton MA
Jin Tang - Canton MA
Assignee:
Genetics Institute, Inc. - Cambridge MA
International Classification:
C07H 2104
US Classification:
4352402
Abstract:
The invention provides a novel calcium-independent cytosolic phospholipase A. sub. 2 /B enzyme, polynucleotides encoding such enzyme and methods for screening unknown compounds for anti-inflammatory activity mediated by the arachidonic acid cascade.