MR. SIDNEY L GOLDFISCHER, M.D.
Osteopathic Medicine at 61 St, New York, NY
License number
New York 089512
Category
Osteopathic Medicine
Type
General Practice
Address
Address
161 WEST 61St St #26C, New York, NY 10023
Phone
(212) 262-0619
Personal information
See more information about SIDNEY L GOLDFISCHER at radaris.comName
Address
Phone
161 W 61St St APT 10B, New York, NY 10023
161 61St St, New York, NY 10023
161 61St St, New York, NY 10023
161 W 61St St #24B, New York, NY 10023
Professional information
Methods Of Improving Therapy Of Perfluorocarbons (Pfc)
US Patent:
2010009, Apr 15, 2010
Filed:
Oct 1, 2009
Appl. No.:
12/587034
Inventors:
Sidney L. Goldfischer - New York NY, US
International Classification:
A61K 31/02, A61P 7/00
US Classification:
514759
Abstract:
This invention describes a novel, two-step method for administering PFC. The first step is designed to block the RES by administration of empty, small, liposomal vesicles (ESV) that are rapidly and preferentially engulfed by macrophages, thereby inhibiting their phagocytosis of subsequently infused PFC emulsions. The second step is the subsequent injection of PFC. ESV are devoid of materials that interfere with the macrophage's metabolic processes and do not impair their ability to clear the circulation of pathogenic organisms. Inhibition of the removal of PFC from the blood stream by the RES will achieve increased circulating PFC, enhanced binding and transport of oxygen throughout the blood stream and consequential reduction of undesirable consequences such as organomegaly and cytokine toxicity.